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Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
Caldwell RD, Qiu H, Askew BC, Bender AT, Brugger N, Camps M, Dhanabal M, Dutt V, Eichhorn T, Gardberg AS, Goutopoulos A, Grenningloh R, Head J, Healey B, Hodous BL, Huck BR, Johnson TL, Jones C, Jones RC, Mochalkin I, Morandi F, Nguyen N, Meyring M, Potnick JR, Santos DC, Schmidt R, Sherer B, Shutes A, Urbahns K, Follis AV, Wegener AA, Zimmerli SC, Liu-Bujalski L. Caldwell RD, et al. Among authors: santos dc. J Med Chem. 2019 Sep 12;62(17):7643-7655. doi: 10.1021/acs.jmedchem.9b00794. Epub 2019 Aug 15. J Med Chem. 2019. PMID: 31368705
Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors.
Xiao Y, Huck BR, Lan R, DeSelm L, Chen X, Qiu H, Neagu C, Johnson T, Mochalkin I, Gardberg A, Jiang X, Tian H, Dutt V, Santos D, Head J, Jackson J, Syed S, Lin J, Wilker E, Ma J, Clark A, Machl A, Bankston D, Jones CCV, Goutopoulos A, Sherer B. Xiao Y, et al. Bioorg Med Chem Lett. 2021 Oct 15;50:128352. doi: 10.1016/j.bmcl.2021.128352. Epub 2021 Sep 2. Bioorg Med Chem Lett. 2021. PMID: 34481987
Corrigendum to "Discovery of 4-aminopyrimidine analogs as highly potent dual P70S6K/Akt inhibitors" [Bioorgan. Med. Chem. Lett. 50 (2021) 128352].
Xiao Y, Huck BR, Lan R, DeSelm L, Chen X, Qiu H, Neagu C, Johnson T, Mochalkin I, Gardberg A, Jiang X, Tian H, Dutt V, Santos D, Head J, Jackson J, Syed S, Lin J, Wilker E, Ma J, Clark A, Machl A, Bankston D, Jones CCV, Goutopoulos A, Sherer B. Xiao Y, et al. Bioorg Med Chem Lett. 2022 Jul 1;67:128758. doi: 10.1016/j.bmcl.2022.128758. Epub 2022 Apr 25. Bioorg Med Chem Lett. 2022. PMID: 35484006 No abstract available.
The landscape of chemokine and cytokine is associated with the distinct clinical status of leprosy patients and their respective household contacts.
Pereira de Oliveira LB, Marçal PHF, Campos KD, Dos Santos DCM, Lima MR, Martins-Filho OA, Brito-de-Sousa JP, Abdala-Torres T, Pinheiro RO, Sarno EN, Fairley JK, Fraga LAO. Pereira de Oliveira LB, et al. Among authors: dos santos dcm. Front Immunol. 2024 Dec 18;15:1476450. doi: 10.3389/fimmu.2024.1476450. eCollection 2024. Front Immunol. 2024. PMID: 39744632 Free PMC article.
Uncontrolled Illegal Mining and Garimpo in the Brazilian Amazon.
Cortinhas Ferreira Neto L, Diniz CG, Maretto RV, Persello C, Silva Pinheiro ML, Castro MC, Sadeck LWR, Filho AF, Cansado J, Souza AAA, Feitosa JP, Santos DC, Adami M, Souza-Filho PWM, Stein A, Biehl A, Klautau A. Cortinhas Ferreira Neto L, et al. Among authors: santos dc. Nat Commun. 2024 Nov 13;15(1):9847. doi: 10.1038/s41467-024-54220-2. Nat Commun. 2024. PMID: 39537611 Free PMC article.
Brazilian Psychiatric Association guidelines for the treatment of Social Anxiety Disorder.
Baldaçara L, Almeida TM, Dos Santos DC, Paschoal AB, Pinto AF, Antonio LAVG, Veiga DL, Loureiro FF, Malloy-Diniz LF, Oliveira RL, Cordeiro Q, Nardi AE, Sanches M, da Silva AG, Uchida RR. Baldaçara L, et al. Among authors: dos santos dc. Braz J Psychiatry. 2024 Nov 11. doi: 10.47626/1516-4446-2024-3878. Online ahead of print. Braz J Psychiatry. 2024. PMID: 39503679 Free article.
277 results