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MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.
Dammert MA, Brägelmann J, Olsen RR, Böhm S, Monhasery N, Whitney CP, Chalishazar MD, Tumbrink HL, Guthrie MR, Klein S, Ireland AS, Ryan J, Schmitt A, Marx A, Ozretić L, Castiglione R, Lorenz C, Jachimowicz RD, Wolf E, Thomas RK, Poirier JT, Büttner R, Sen T, Byers LA, Reinhardt HC, Letai A, Oliver TG, Sos ML. Dammert MA, et al. Among authors: whitney cp. Nat Commun. 2019 Aug 2;10(1):3485. doi: 10.1038/s41467-019-11371-x. Nat Commun. 2019. PMID: 31375684 Free PMC article.
ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer.
Olsen RR, Ireland AS, Kastner DW, Groves SM, Spainhower KB, Pozo K, Kelenis DP, Whitney CP, Guthrie MR, Wait SJ, Soltero D, Witt BL, Quaranta V, Johnson JE, Oliver TG. Olsen RR, et al. Among authors: whitney cp. Genes Dev. 2021 Jun;35(11-12):847-869. doi: 10.1101/gad.348295.121. Epub 2021 May 20. Genes Dev. 2021. PMID: 34016693 Free PMC article.