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The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake.
Jensen CH, Kosmina R, Rydén M, Baun C, Hvidsten S, Andersen MS, Christensen LL, Gastaldelli A, Marraccini P, Arner P, Jørgensen CD, Laborda J, Holst JJ, Andersen DC. Jensen CH, et al. Among authors: laborda j. EBioMedicine. 2019 Aug;46:368-380. doi: 10.1016/j.ebiom.2019.07.070. Epub 2019 Aug 3. EBioMedicine. 2019. PMID: 31383551 Free PMC article.
The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities.
Sánchez-Solana B, Nueda ML, Ruvira MD, Ruiz-Hidalgo MJ, Monsalve EM, Rivero S, García-Ramírez JJ, Díaz-Guerra MJ, Baladrón V, Laborda J. Sánchez-Solana B, et al. Among authors: laborda j. Biochim Biophys Acta. 2011 Jun;1813(6):1153-64. doi: 10.1016/j.bbamcr.2011.03.004. Epub 2011 Mar 15. Biochim Biophys Acta. 2011. PMID: 21419176 Free article.
Different expression levels of DLK1 inversely modulate the oncogenic potential of human MDA-MB-231 breast cancer cells through inhibition of NOTCH1 signaling.
Nueda ML, Naranjo AI, Baladrón V, Laborda J. Nueda ML, et al. Among authors: laborda j. FASEB J. 2017 Aug;31(8):3484-3496. doi: 10.1096/fj.201601341RRR. Epub 2017 May 1. FASEB J. 2017. PMID: 28461338
-Nueda, M.-L., Naranjo, A.-I., Baladron V., Laborda, J. Different expression levels of DLK1 inversely modulate the oncogenic potential of human MDA-MB-231 breast cancer cells through inhibition of NOTCH1 signaling....
-Nueda, M.-L., Naranjo, A.-I., Baladron V., Laborda, J. Different expression levels of DLK1 inversely modulate the oncogenic p …
94 results