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Lipoprotein Lipase Up-regulation in Hepatic Stellate Cells Exacerbates Liver Fibrosis in Nonalcoholic Steatohepatitis in Mice.
Teratani T, Tomita K, Furuhashi H, Sugihara N, Higashiyama M, Nishikawa M, Irie R, Takajo T, Wada A, Horiuchi K, Inaba K, Hanawa Y, Shibuya N, Okada Y, Kurihara C, Nishii S, Mizoguchi A, Hozumi H, Watanabe C, Komoto S, Nagao S, Yamamoto J, Miura S, Hokari R, Kanai T. Teratani T, et al. Among authors: watanabe c. Hepatol Commun. 2019 Jun 6;3(8):1098-1112. doi: 10.1002/hep4.1383. eCollection 2019 Aug. Hepatol Commun. 2019. PMID: 31388630 Free PMC article.
Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H, Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R, Kanai T, Miura S, Hibi T. Tomita K, et al. Among authors: watanabe c. Hepatology. 2014 Jan;59(1):154-69. doi: 10.1002/hep.26604. Epub 2013 Nov 18. Hepatology. 2014. PMID: 23832448
Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells.
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Usui S, Furuhashi H, Kimura A, Nishiyama K, Maejima T, Okada Y, Kurihara C, Shimamura K, Ebinuma H, Saito H, Yokoyama H, Watanabe C, Komoto S, Nagao S, Sugiyama K, Aosasa S, Hatsuse K, Yamamoto J, Hibi T, Miura S, Hokari R, Kanai T. Tomita K, et al. Among authors: watanabe c. J Hepatol. 2014 Jul;61(1):98-106. doi: 10.1016/j.jhep.2014.03.018. Epub 2014 Mar 18. J Hepatol. 2014. PMID: 24657401
Vitamin A-coupled liposome system targeting free cholesterol accumulation in hepatic stellate cells offers a beneficial therapeutic strategy for liver fibrosis.
Furuhashi H, Tomita K, Teratani T, Shimizu M, Nishikawa M, Higashiyama M, Takajo T, Shirakabe K, Maruta K, Okada Y, Kurihara C, Watanabe C, Komoto S, Aosasa S, Nagao S, Yamamoto J, Miura S, Hokari R. Furuhashi H, et al. Among authors: watanabe c. Hepatol Res. 2018 Apr;48(5):397-407. doi: 10.1111/hepr.13040. Epub 2018 Jan 10. Hepatol Res. 2018. PMID: 29243365
Chitinase 3-like 1 deficiency ameliorates liver fibrosis by promoting hepatic macrophage apoptosis.
Higashiyama M, Tomita K, Sugihara N, Nakashima H, Furuhashi H, Nishikawa M, Inaba K, Wada A, Horiuchi K, Hanawa Y, Shibuya N, Kurihara C, Okada Y, Nishii S, Mizoguchi A, Hozumi H, Watanabe C, Komoto S, Yamamoto J, Seki S, Miura S, Hokari R. Higashiyama M, et al. Among authors: watanabe c. Hepatol Res. 2019 Nov;49(11):1316-1328. doi: 10.1111/hepr.13396. Epub 2019 Jul 12. Hepatol Res. 2019. PMID: 31250532 Free PMC article.
Angiopoietin-like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells.
Teratani T, Tomita K, Wada A, Sugihara N, Higashiyama M, Inaba K, Horiuchi K, Hanawa Y, Nishii S, Mizoguchi A, Tanemoto R, Ito S, Okada Y, Kurihara C, Akita Y, Narimatsu K, Watanabe C, Komoto S, Oike Y, Miura S, Hokari R, Kanai T. Teratani T, et al. Among authors: watanabe c. Hepatol Res. 2021 May;51(5):580-592. doi: 10.1111/hepr.13603. Epub 2021 Apr 7. Hepatol Res. 2021. PMID: 33247991
Physiological stress exacerbates murine colitis by enhancing proinflammatory cytokine expression that is dependent on IL-18.
Matsunaga H, Hokari R, Ueda T, Kurihara C, Hozumi H, Higashiyama M, Okada Y, Watanabe C, Komoto S, Nakamura M, Kawaguchi A, Nagao S, Sekiyama A, Miura S. Matsunaga H, et al. Among authors: watanabe c. Am J Physiol Gastrointest Liver Physiol. 2011 Sep;301(3):G555-64. doi: 10.1152/ajpgi.00482.2010. Epub 2011 Jun 30. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21719737 Free article.
972 results