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The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease.
Nanto-Hara F, Kanemitsu Y, Fukuda S, Kikuchi K, Asaji K, Saigusa D, Iwasaki T, Ho HJ, Mishima E, Suzuki T, Suzuki C, Tsukimi T, Matsuhashi T, Oikawa Y, Akiyama Y, Kure S, Owada Y, Tomioka Y, Soga T, Ito S, Abe T. Nanto-Hara F, et al. Among authors: saigusa d. Nephrol Dial Transplant. 2020 Feb 1;35(2):250-264. doi: 10.1093/ndt/gfz126. Nephrol Dial Transplant. 2020. PMID: 31411705
4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade.
Al Rahim M, Nakajima A, Saigusa D, Tetsu N, Maruyama Y, Shibuya M, Yamakoshi H, Tomioka Y, Iwabuchi Y, Ohizumi Y, Yamakuni T. Al Rahim M, et al. Among authors: saigusa d. Biochemistry. 2009 Aug 18;48(32):7713-21. doi: 10.1021/bi901088w. Biochemistry. 2009. PMID: 19601643
Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry.
Saigusa D, Shiba K, Inoue A, Hama K, Okutani M, Iida N, Saito M, Suzuki K, Kaneko T, Suzuki N, Yamaguchi H, Mano N, Goto J, Hishinuma T, Aoki J, Tomioka Y. Saigusa D, et al. Anal Bioanal Chem. 2012 Jun;403(7):1897-905. doi: 10.1007/s00216-012-6004-9. Epub 2012 Apr 27. Anal Bioanal Chem. 2012. PMID: 22538778
Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3.
Akiyama Y, Kikuchi K, Saigusa D, Suzuki T, Takeuchi Y, Mishima E, Yamamoto Y, Ishida A, Sugawara D, Jinno D, Shima H, Toyohara T, Suzuki C, Souma T, Moriguchi T, Tomioka Y, Ito S, Abe T. Akiyama Y, et al. Among authors: saigusa d. PLoS One. 2013 Jul 9;8(7):e66518. doi: 10.1371/journal.pone.0066518. Print 2013. PLoS One. 2013. PMID: 23874392 Free PMC article.
133 results