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The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells.
Jacoupy M, Hamon-Keromen E, Ordureau A, Erpapazoglou Z, Coge F, Corvol JC, Nosjean O, Mannoury la Cour C, Millan MJ, Boutin JA, Harper JW, Brice A, Guedin D, Gautier CA, Corti O. Jacoupy M, et al. Among authors: gautier ca. Sci Rep. 2019 Aug 14;9(1):11829. doi: 10.1038/s41598-019-47352-9. Sci Rep. 2019. PMID: 31413265 Free PMC article.
Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10.
Bertolin G, Jacoupy M, Traver S, Ferrando-Miguel R, Saint Georges T, Grenier K, Ardila-Osorio H, Muriel MP, Takahashi H, Lees AJ, Gautier C, Guedin D, Coge F, Fon EA, Brice A, Corti O. Bertolin G, et al. Cell Death Differ. 2015 Oct;22(10):1563-76. doi: 10.1038/cdd.2014.224. Epub 2015 Jan 16. Cell Death Differ. 2015. PMID: 25591737 Free PMC article.
NF-κB pathway controls mitochondrial dynamics.
Laforge M, Rodrigues V, Silvestre R, Gautier C, Weil R, Corti O, Estaquier J. Laforge M, et al. Cell Death Differ. 2016 Jan;23(1):89-98. doi: 10.1038/cdd.2015.42. Epub 2015 May 29. Cell Death Differ. 2016. PMID: 26024391 Free PMC article.
Mitochondrial dysfunctions in Parkinson's disease.
Gautier CA, Corti O, Brice A. Gautier CA, et al. Rev Neurol (Paris). 2014 May;170(5):339-43. doi: 10.1016/j.neurol.2013.06.003. Epub 2013 Oct 9. Rev Neurol (Paris). 2014. PMID: 24119854 Review.
Tissue- and cell-specific mitochondrial defect in Parkin-deficient mice.
Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A. Damiano M, et al. Among authors: gautier ca. PLoS One. 2014 Jun 24;9(6):e99898. doi: 10.1371/journal.pone.0099898. eCollection 2014. PLoS One. 2014. PMID: 24959870 Free PMC article.
Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE.
Nava C, Lamari F, Héron D, Mignot C, Rastetter A, Keren B, Cohen D, Faudet A, Bouteiller D, Gilleron M, Jacquette A, Whalen S, Afenjar A, Périsse D, Laurent C, Dupuits C, Gautier C, Gérard M, Huguet G, Caillet S, Leheup B, Leboyer M, Gillberg C, Delorme R, Bourgeron T, Brice A, Depienne C. Nava C, et al. Transl Psychiatry. 2012 Oct 23;2(10):e179. doi: 10.1038/tp.2012.102. Transl Psychiatry. 2012. PMID: 23092983 Free PMC article.
24 results