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Replicated evidence that endophenotypic expression of schizophrenia polygenic risk is greater in healthy siblings of patients compared to controls, suggesting gene-environment interaction. The EUGEI study.
van Os J, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome Investigators (GROUP); Arango C, O'Donovan M, Rutten BPF, Guloksuz S. van Os J, et al. Among authors: akdede b. Psychol Med. 2020 Aug;50(11):1884-1897. doi: 10.1017/S003329171900196X. Epub 2019 Aug 15. Psychol Med. 2020. PMID: 31414981
Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum.
Pries LK, Dal Ferro GA, van Os J, Delespaul P, Kenis G, Lin BD, Luykx JJ, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Şahin Cankurtaran E, Ulusoy Kaymak S, Mihaljevic MM, Andric Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Can Saka M; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Arango C, O'Donovan M, Tosato S, Rutten BPF, Guloksuz S. Pries LK, et al. Among authors: akdede b. Epidemiol Psychiatr Sci. 2020 Nov 17;29:e182. doi: 10.1017/S2045796020000943. Epidemiol Psychiatr Sci. 2020. PMID: 33200977 Free PMC article.
Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study.
Guloksuz S, Pries LK, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran E, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşog Lu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Arango C, O'Donovan M, Rutten BPF, van Os J. Guloksuz S, et al. Among authors: akdede b. World Psychiatry. 2019 Jun;18(2):173-182. doi: 10.1002/wps.20629. World Psychiatry. 2019. PMID: 31059627 Free PMC article.
Estimating Exposome Score for Schizophrenia Using Predictive Modeling Approach in Two Independent Samples: The Results From the EUGEI Study.
Pries LK, Lage-Castellanos A, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altinyazar V, Yalinçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Cabrera B, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Arango C, O'Donovan M, Rutten BPF, van Os J, Guloksuz S. Pries LK, et al. Among authors: akdede b. Schizophr Bull. 2019 Sep 11;45(5):960-965. doi: 10.1093/schbul/sbz054. Schizophr Bull. 2019. PMID: 31508804 Free PMC article.
A replication study of JTC bias, genetic liability for psychosis and delusional ideation.
Henquet C, van Os J, Pries LK, Rauschenberg C, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran ES, Kaymak SU, Mihaljevic MM, Petrovic SS, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC, Arango C, O'Donovan M, Rutten BPF, Gülöksüz S. Henquet C, et al. Among authors: akdede b. Psychol Med. 2022 Jul;52(9):1777-1783. doi: 10.1017/S0033291720003578. Epub 2020 Oct 13. Psychol Med. 2022. PMID: 33046166 Free PMC article.
Evidence, and replication thereof, that molecular-genetic and environmental risks for psychosis impact through an affective pathway.
van Os J, Pries LK, Ten Have M, de Graaf R, van Dorsselaer S, Delespaul P, Bak M, Kenis G, Lin BD, Luykx JJ, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Petrovic SA, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC, Arango C, O'Donovan M, Rutten BPF, Guloksuz S. van Os J, et al. Among authors: akdede b. Psychol Med. 2022 Jul;52(10):1910-1922. doi: 10.1017/S0033291720003748. Epub 2020 Oct 19. Psychol Med. 2022. PMID: 33070791
Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings.
Velthorst E, Mollon J, Murray RM, de Haan L, Germeys IM, Glahn DC, Arango C, van der Ven E, Di Forti M, Bernardo M, Guloksuz S, Delespaul P, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Santos JL, Jiménez-López E, Sanjuan J, Aguilar EJ, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Atbaşoğlu C, Saka MC, Üçok A, Alptekin K, Akdede B, Binbay T, Altınyazar V, Ulaş H, Yalınçetin B, Gümüş-Akay G, Beyaz BC, Soygür H, Cankurtaran EŞ, Kaymak SU, Maric NP, Mihaljevic MM, Petrovic SA, Mirjanic T, Del-Ben CM, Ferraro L, Gayer-Anderson C, Jones PB, Jongsma HE, Kirkbride JB, La Cascia C, Lasalvia A, Tosato S, Llorca PM, Menezes PR, Morgan C, Quattrone D, Menchetti M, Selten JP, Szöke A, Tarricone I, Tortelli A, McGuire P, Valmaggia L, Kempton MJ, van der Gaag M, Riecher-Rössler A, Bressan RA, Barrantes-Vidal N, Nelson B, McGorry P, Pantelis C, Krebs MO, Ruhrmann S, Sachs G, Rutten BPF, van Os J, Alizadeh BZ, van Amelsvoort T, Bartels-Velthuis AA, Bruggeman R, van Beveren NJ, Luykx JJ, Cahn W, Simons CJP, Kahn RS, Schirmbeck F, van Winkel R; EU-GEI High Risk Study; Reichenberg A. Velthorst E, et al. Among authors: akdede b. Mol Psychiatry. 2021 Aug;26(8):4529-4543. doi: 10.1038/s41380-020-00969-z. Epub 2021 Jan 7. Mol Psychiatry. 2021. PMID: 33414498
Examining the association between exposome score for schizophrenia and functioning in schizophrenia, siblings, and healthy controls: Results from the EUGEI study.
Erzin G, Pries LK, van Os J, Fusar-Poli L, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Ucok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Arango C, O'Donovan MC, Rutten BPF, Guloksuz S. Erzin G, et al. Among authors: akdede b. Eur Psychiatry. 2021 Mar 19;64(1):e25. doi: 10.1192/j.eurpsy.2021.19. Eur Psychiatry. 2021. PMID: 33736735 Free PMC article.
Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study.
Fusar-Poli L, Pries LK, van Os J, Erzin G, Delespaul P, Kenis G, Luykx JJ, Lin BD, Richards AL, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Üçok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Aguglia E, Arango C, O'Donovan M, Rutten BPF, Guloksuz S. Fusar-Poli L, et al. Among authors: akdede b. Prog Neuropsychopharmacol Biol Psychiatry. 2022 Mar 8;113:110440. doi: 10.1016/j.pnpbp.2021.110440. Epub 2021 Sep 16. Prog Neuropsychopharmacol Biol Psychiatry. 2022. PMID: 34536513 Free article.
The association between cannabis use and facial emotion recognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study.
Fusar-Poli L, Pries LK, van Os J, Radhakrishnan R, Pençe AY, Erzin G, Delespaul P, Kenis G, Luykx JJ, Lin BD, Akdede B, Binbay T, Altınyazar V, Yalınçetin B, Gümüş-Akay G, Cihan B, Soygür H, Ulaş H, Cankurtaran EŞ, Kaymak SU, Mihaljevic MM, Andric-Petrovic S, Mirjanic T, Bernardo M, Mezquida G, Amoretti S, Bobes J, Saiz PA, García-Portilla MP, Sanjuan J, Aguilar EJ, Santos JL, Jiménez-López E, Arrojo M, Carracedo A, López G, González-Peñas J, Parellada M, Maric NP, Atbaşoğlu C, Üçok A, Alptekin K, Saka MC; Genetic Risk and Outcome of Psychosis (GROUP) investigators; Aguglia E, Arango C, Rutten BP, Guloksuz S. Fusar-Poli L, et al. Among authors: akdede b. Eur Neuropsychopharmacol. 2022 Oct;63:47-59. doi: 10.1016/j.euroneuro.2022.08.003. Epub 2022 Aug 30. Eur Neuropsychopharmacol. 2022. PMID: 36055075 Free article.
58 results