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Page 1
Catalytically Impaired TYK2 Variants are Protective Against Childhood- and Adult-Onset Systemic Lupus Erythematosus in Mexicans.
Contreras-Cubas C, García-Ortiz H, Velázquez-Cruz R, Barajas-Olmos F, Baca P, Martínez-Hernández A, Barbosa-Cobos RE, Ramírez-Bello J, López-Hernández MA, Svyryd Y, Mutchinick OM, Baca V, Orozco L. Contreras-Cubas C, et al. Sci Rep. 2019 Aug 21;9(1):12165. doi: 10.1038/s41598-019-48451-3. Sci Rep. 2019. PMID: 31434951 Free PMC article.
Association of HMOX1 and NQO1 Polymorphisms with Metabolic Syndrome Components.
Martínez-Hernández A, Córdova EJ, Rosillo-Salazar O, García-Ortíz H, Contreras-Cubas C, Islas-Andrade S, Revilla-Monsalve C, Salas-Labadía C, Orozco L. Martínez-Hernández A, et al. PLoS One. 2015 May 1;10(5):e0123313. doi: 10.1371/journal.pone.0123313. eCollection 2015. PLoS One. 2015. PMID: 25933176 Free PMC article.
Gender-Dependent Association of FTO Polymorphisms with Body Mass Index in Mexicans.
Saldaña-Alvarez Y, Salas-Martínez MG, García-Ortiz H, Luckie-Duque A, García-Cárdenas G, Vicenteño-Ayala H, Cordova EJ, Esparza-Aguilar M, Contreras-Cubas C, Carnevale A, Chávez-Saldaña M, Orozco L. Saldaña-Alvarez Y, et al. PLoS One. 2016 Jan 4;11(1):e0145984. doi: 10.1371/journal.pone.0145984. eCollection 2016. PLoS One. 2016. PMID: 26726774 Free PMC article.
Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico.
Contreras-Cubas C, Sánchez-Hernández BE, García-Ortiz H, Martínez-Hernández A, Barajas-Olmos F, Cid M, Mendoza-Caamal EC, Centeno-Cruz F, Ortiz-Cruz G, Jiménez-López JC, Córdova EJ, Salas-Bautista EG, Saldaña-Alvarez Y, Fernández-López JC, Mutchinick OM, Orozco L. Contreras-Cubas C, et al. PLoS One. 2016 Sep 20;11(9):e0163248. doi: 10.1371/journal.pone.0163248. eCollection 2016. PLoS One. 2016. PMID: 27649570 Free PMC article.
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams AL, Bonàs-Guarch S, Hartl C, Ripke S; Diabetes Prevention Program Research Group; Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza-Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz-Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L, Arellano-Campos O, Riba L, Harden M; Broad Genomics Platform; Gabriel S; T2D-GENES Consortium; Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC; SIGMA T2D Genetics Consortium. Mercader JM, et al. Diabetes. 2017 Nov;66(11):2903-2914. doi: 10.2337/db17-0187. Epub 2017 Aug 24. Diabetes. 2017. PMID: 28838971 Free PMC article.
Gene variants in AKT1, GCKR and SOCS3 are differentially associated with metabolic traits in Mexican Amerindians and Mestizos.
Cid-Soto MA, Martínez-Hernández A, García-Ortíz H, Córdova EJ, Barajas-Olmos F, Centeno-Cruz F, Contreras-Cubas C, Mendoza-Caamal EC, Ciceron-Arellano I, Morales-Rivera MI, Jimenez-Ruiz JL, Salas-Martínez G, Saldaña-Álvarez Y, Revilla-Monsalve C, Islas-Andrade S, Orozco L. Cid-Soto MA, et al. Gene. 2018 Dec 30;679:160-171. doi: 10.1016/j.gene.2018.08.076. Epub 2018 Aug 31. Gene. 2018. PMID: 30176313
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Córdova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, García-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jørgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martínez-Hernández A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O'Dushlaine C, Payne AJ, Pihoker C; Broad Genomics Platform; Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberón X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, Kwak SH… See abstract for full author list ➔ Flannick J, et al. Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22. Nature. 2019. PMID: 31118516 Free PMC article.
Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population.
Salas-Martínez MG, Saldaña-Alvarez Y, Cordova EJ, Mendiola-Soto DK, Cid-Soto MA, Luckie-Duque A, Vicenteño-Ayala H, Barajas-Olmos F, Contreras-Cubas C, García-Ortiz H, Jiménez-Ruíz JL, Centeno-Cruz F, Martínez-Hernández A, Mendoza-Caamal EC, Mirzaeicheshmeh E, Orozco L. Salas-Martínez MG, et al. PLoS One. 2019 Dec 2;14(12):e0225030. doi: 10.1371/journal.pone.0225030. eCollection 2019. PLoS One. 2019. PMID: 31790415 Free PMC article.
36 results