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POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients.
Baird RD, van Rossum AGJ, Oliveira M, Beelen K, Gao M, Schrier M, Mandjes IAM, Garcia-Corbacho J, Vallier AL, Dougall G, van Werkhoven E, Linossi C, Kumar S, van Tinteren H, Callari M, Beddowes E, Perez-Garcia JM, Rosing H, Platte E, Nederlof P, Schot M, de Vries Schultink A, Bernards R, Saura C, Gallagher W, Cortès J, Caldas C, Linn SC. Baird RD, et al. Clin Cancer Res. 2019 Nov 15;25(22):6598-6605. doi: 10.1158/1078-0432.CCR-19-0508. Epub 2019 Aug 22. Clin Cancer Res. 2019. PMID: 31439579 Clinical Trial.
The beautiful history of pertuzumab.
Perez-Garcia J, Muñoz-Couselo E, Ortega V, Cortes J. Perez-Garcia J, et al. Expert Rev Anticancer Ther. 2012 Jun;12(6):703-5. doi: 10.1586/era.12.46. Expert Rev Anticancer Ther. 2012. PMID: 22716485 No abstract available.
Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.
Dienstmann R, Serpico D, Rodon J, Saura C, Macarulla T, Elez E, Alsina M, Capdevila J, Perez-Garcia J, Sánchez-Ollé G, Aura C, Prudkin L, Landolfi S, Hernández-Losa J, Vivancos A, Tabernero J. Dienstmann R, et al. Mol Cancer Ther. 2012 Sep;11(9):2062-71. doi: 10.1158/1535-7163.MCT-12-0290. Epub 2012 Jun 21. Mol Cancer Ther. 2012. PMID: 22723336
A roadmap for accelerated drug approval in breast cancer?
Perez-Garcia J, Cortes J. Perez-Garcia J, et al. Lancet Oncol. 2012 Sep;13(9):850-1. doi: 10.1016/S1470-2045(12)70367-4. Epub 2012 Aug 9. Lancet Oncol. 2012. PMID: 22884504 No abstract available.
Targeting FGFR with dovitinib (TKI258): preclinical and clinical data in breast cancer.
André F, Bachelot T, Campone M, Dalenc F, Perez-Garcia JM, Hurvitz SA, Turner N, Rugo H, Smith JW, Deudon S, Shi M, Zhang Y, Kay A, Porta DG, Yovine A, Baselga J. André F, et al. Clin Cancer Res. 2013 Jul 1;19(13):3693-702. doi: 10.1158/1078-0432.CCR-13-0190. Epub 2013 May 8. Clin Cancer Res. 2013. PMID: 23658459 Clinical Trial.
Adjuvant bevacizumab: positive data from a negative trial.
Perez-Garcia J, Cortes J. Perez-Garcia J, et al. Lancet Oncol. 2013 Sep;14(10):910-1. doi: 10.1016/S1470-2045(13)70378-4. Epub 2013 Aug 7. Lancet Oncol. 2013. PMID: 23932547 No abstract available.
149 results