Kanthasamy A - Search Results

1

Fyn amplifies NLRP3 inflammasome signaling in Parkinson's disease.

Panicker N, Kanthasamy A, Kanthasamy AG. Panicker N, et al. Among authors: kanthasamy a, kanthasamy ag. Aging (Albany NY). 2019 Aug 27;11(16):5871-5873. doi: 10.18632/aging.102210. Epub 2019 Aug 27. Aging (Albany NY). 2019. PMID: 31454793 Free PMC article. No abstract available.

2

Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.

Kaul S, Kanthasamy A, Kitazawa M, Anantharam V, Kanthasamy AG. Kaul S, et al. Among authors: kanthasamy a, kanthasamy ag. Eur J Neurosci. 2003 Sep;18(6):1387-401. doi: 10.1046/j.1460-9568.2003.02864.x. Eur J Neurosci. 2003. PMID: 14511319

3

Role of proteolytic activation of protein kinase Cdelta in oxidative stress-induced apoptosis.

Kanthasamy AG, Kitazawa M, Kanthasamy A, Anantharam V. Kanthasamy AG, et al. Among authors: kanthasamy a. Antioxid Redox Signal. 2003 Oct;5(5):609-20. doi: 10.1089/152308603770310275. Antioxid Redox Signal. 2003. PMID: 14580317 Review.

4

Dieldrin promotes proteolytic cleavage of poly(ADP-ribose) polymerase and apoptosis in dopaminergic cells: protective effect of mitochondrial anti-apoptotic protein Bcl-2.

Kitazawa M, Anantharam V, Kanthasamy A, Kanthasamy AG. Kitazawa M, et al. Among authors: kanthasamy a, kanthasamy ag. Neurotoxicology. 2004 Jun;25(4):589-98. doi: 10.1016/j.neuro.2003.09.014. Neurotoxicology. 2004. PMID: 15183012

5

Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.

Kitazawa M, Anantharam V, Yang Y, Hirata Y, Kanthasamy A, Kanthasamy AG. Kitazawa M, et al. Among authors: kanthasamy a, kanthasamy ag. Biochem Pharmacol. 2005 Jan 1;69(1):133-46. doi: 10.1016/j.bcp.2004.08.035. Biochem Pharmacol. 2005. PMID: 15588722

6

Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.

Latchoumycandane C, Anantharam V, Kitazawa M, Yang Y, Kanthasamy A, Kanthasamy AG. Latchoumycandane C, et al. Among authors: kanthasamy a, kanthasamy ag. J Pharmacol Exp Ther. 2005 Apr;313(1):46-55. doi: 10.1124/jpet.104.078469. Epub 2004 Dec 17. J Pharmacol Exp Ther. 2005. PMID: 15608081

7

Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.

Anantharam V, Kitazawa M, Latchoumycandane C, Kanthasamy A, Kanthasamy AG. Anantharam V, et al. Among authors: kanthasamy a, kanthasamy ag. Ann N Y Acad Sci. 2004 Dec;1035:271-89. doi: 10.1196/annals.1332.017. Ann N Y Acad Sci. 2004. PMID: 15681813

8

Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.

Kaul S, Anantharam V, Yang Y, Choi CJ, Kanthasamy A, Kanthasamy AG. Kaul S, et al. Among authors: kanthasamy a, kanthasamy ag. J Biol Chem. 2005 Aug 5;280(31):28721-30. doi: 10.1074/jbc.M501092200. Epub 2005 Jun 16. J Biol Chem. 2005. PMID: 15961393 Free article.

Recently, we demonstrated that protein kinase C-delta (PKCdelta) is an oxidative stress-sensitive kinase that can be activated by caspase-3-dependent proteolytic cleavage to induce apoptotic cell death in cell culture models of Parkinson disease (Kaul, S., Kanthasamy, A …

Recently, we demonstrated that protein kinase C-delta (PKCdelta) is an oxidative stress-sensitive kinase that can be activated by caspase-3- …

9

Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.

Kaul S, Anantharam V, Kanthasamy A, Kanthasamy AG. Kaul S, et al. Among authors: kanthasamy a, kanthasamy ag. Brain Res Mol Brain Res. 2005 Sep 13;139(1):137-52. doi: 10.1016/j.molbrainres.2005.05.022. Brain Res Mol Brain Res. 2005. PMID: 15978696

10

Dieldrin induces ubiquitin-proteasome dysfunction in alpha-synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death.

Sun F, Anantharam V, Latchoumycandane C, Kanthasamy A, Kanthasamy AG. Sun F, et al. Among authors: kanthasamy a, kanthasamy ag. J Pharmacol Exp Ther. 2005 Oct;315(1):69-79. doi: 10.1124/jpet.105.084632. Epub 2005 Jun 29. J Pharmacol Exp Ther. 2005. PMID: 15987830

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