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Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasis.
Ortega-Gonzalez P, Taylor G, Jangra RK, Tenorio R, Fernandez de Castro I, Mainou BA, Orchard RC, Wilen CB, Brigleb PH, Sojati J, Chandran K, Sachse M, Risco C, Dermody TS. Ortega-Gonzalez P, et al. Among authors: brigleb ph. PLoS Pathog. 2022 Mar 9;18(3):e1010322. doi: 10.1371/journal.ppat.1010322. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35263388 Free PMC article.
Neural-Cell-Intrinsic NF-κB Signaling Enhances Reovirus Virulence.
Taylor GM, Pruijssers AJ, Brigleb PH, Fiske KL, Shang P, Urbanek K, Brown JJ, Rajasundaram D, Dermody TS. Taylor GM, et al. Among authors: brigleb ph. J Virol. 2023 Jan 31;97(1):e0144222. doi: 10.1128/jvi.01442-22. Epub 2022 Dec 21. J Virol. 2023. PMID: 36541803 Free PMC article.
The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells.
Medina Sanchez L, Siller M, Zeng Y, Brigleb PH, Sangani KA, Soto AS, Engl C, Laughlin CR, Rana M, Van Der Kraak L, Pandey SP, Bender MJ, Fitzgerald B, Hedden L, Fiske K, Taylor GM, Wright AP, Mehta ID, Rahman SA, Galipeau HJ, Mullett SJ, Gelhaus SL, Watkins SC, Bercik P, Nice TJ, Jabri B, Meisel M, Das J, Dermody TS, Verdú EF, Hinterleitner R. Medina Sanchez L, et al. Among authors: brigleb ph. Immunity. 2023 Aug 8;56(8):1862-1875.e9. doi: 10.1016/j.immuni.2023.06.022. Epub 2023 Jul 20. Immunity. 2023. PMID: 37478853 Free PMC article.
Intraductal infection with H5N1 clade 2.3.4.4b influenza virus.
Roubidoux EK, Meliopoulos V, Livingston B, Brigleb PH, Schultz-Cherry S. Roubidoux EK, et al. Among authors: brigleb ph. bioRxiv [Preprint]. 2024 Nov 2:2024.11.01.621606. doi: 10.1101/2024.11.01.621606. bioRxiv. 2024. PMID: 39554179 Free PMC article. Preprint.
Immune History Modifies Disease Severity to HPAI H5N1 Clade 2.3.4.4b Viral Challenge.
Brigleb PH, Sharp B, Roubidoux EK, Meliopoulos V, Tan S, Livingston B, Morris D, Ripperger T, Lazure L, Balaraman V, Thompson AC, Kleinhenz K, Dimitrov K, Thomas PG, Schultz-Cherry S. Brigleb PH, et al. bioRxiv [Preprint]. 2024 Oct 23:2024.10.23.619695. doi: 10.1101/2024.10.23.619695. bioRxiv. 2024. PMID: 39484458 Free PMC article. Preprint.
18 results