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Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei.
Pereira GA, Santos LH, Wang SC, Martins LC, Villela FS, Liao W, Dessoy MA, Dias LC, Andricopulo AD, Costa MA, Nagem RA, Caffrey CR, Liedl KR, Caffarena ER, Ferreira RS. Pereira GA, et al. Among authors: martins lc. Future Med Chem. 2019 Jul;11(13):1537-1551. doi: 10.4155/fmc-2018-0523. Future Med Chem. 2019. PMID: 31469332 Free PMC article.
Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'.
Pereira GAN, da Silva EB, Braga SFP, Leite PG, Martins LC, Vieira RP, Soh WT, Villela FS, Costa FMR, Ray D, de Andrade SF, Brandstetter H, Oliveira RB, Caffrey CR, Machado FS, Ferreira RS. Pereira GAN, et al. Among authors: martins lc. Eur J Med Chem. 2019 Oct 1;179:765-778. doi: 10.1016/j.ejmech.2019.06.062. Epub 2019 Jun 22. Eur J Med Chem. 2019. PMID: 31284086 Free PMC article.
Synthesis of quinoline derivatives as potential cysteine protease inhibitors.
Andrade MM, Martins LC, Marques GV, Silva CA, Faria G, Caldas S, Dos Santos JS, Leclercq SY, Maltarollo VG, Ferreira RS, Oliveira RB. Andrade MM, et al. Among authors: martins lc. Future Med Chem. 2020 Apr;12(7):571-581. doi: 10.4155/fmc-2019-0201. Epub 2020 Mar 2. Future Med Chem. 2020. PMID: 32116030
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity.
Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, Huang XP, Kumar JM, Robertson MJ, Panova O, Seven AB, Wetsel AQ, Wetsel WC, Irwin JJ, Skiniotis G, Shoichet BK, Roth BL, Ellman JA. Kaplan AL, et al. Among authors: martins lc. Nature. 2022 Oct;610(7932):582-591. doi: 10.1038/s41586-022-05258-z. Epub 2022 Sep 28. Nature. 2022. PMID: 36171289 Free PMC article.
300 results