Miyawaki I - Search Results

1

Physiological and drug-induced changes in blood levels of adrenal steroids and their precursors in cynomolgus monkeys: An application of steroid profiling by LC-MS/MS for evaluation of the adrenal toxicity.

Tochitani T, Yamashita A, Matsumoto I, Kouchi M, Fujii Y, Yamada T, Miyawaki I. Tochitani T, et al. Among authors: miyawaki i. J Toxicol Sci. 2019;44(9):575-584. doi: 10.2131/jts.44.575. J Toxicol Sci. 2019. PMID: 31474739 Free article.

2

Toxicological approach for elucidation of clobazam-induced hepatomegaly in male rats.

Miyawaki I, Matsumoto I, Horie H, Inada H, Kimura J, Funabashi H, Seki T. Miyawaki I, et al. Regul Toxicol Pharmacol. 2011 Aug;60(3):323-31. doi: 10.1016/j.yrtph.2011.04.009. Epub 2011 May 7. Regul Toxicol Pharmacol. 2011. PMID: 21575666

3

Evaluation of ovarian toxicity of mono-(2-ethylhexyl) phthalate (MEHP) using cultured rat ovarian follicles.

Inada H, Chihara K, Yamashita A, Miyawaki I, Fukuda C, Tateishi Y, Kunimatsu T, Kimura J, Funabashi H, Miyano T. Inada H, et al. Among authors: miyawaki i. J Toxicol Sci. 2012;37(3):483-90. doi: 10.2131/jts.37.483. J Toxicol Sci. 2012. PMID: 22687988 Free article.

4

Evaluation of ovarian toxicity of sodium valproate (VPA) using cultured rat ovarian follicles.

Inada H, Chihara K, Yamashita A, Miyawaki I, Fukuda C, Tateishi Y, Kunimatsu T, Kimura J, Funabashi H, Miyano T. Inada H, et al. Among authors: miyawaki i. J Toxicol Sci. 2012;37(3):587-94. doi: 10.2131/jts.37.587. J Toxicol Sci. 2012. PMID: 22687998 Free article.

5

The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance-associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy.

Miyawaki I, Tamura A, Matsumoto I, Inada H, Kunimatsu T, Kimura J, Funabashi H. Miyawaki I, et al. Toxicol Appl Pharmacol. 2012 Dec 15;265(3):351-9. doi: 10.1016/j.taap.2012.09.003. Epub 2012 Sep 12. Toxicol Appl Pharmacol. 2012. PMID: 22982618

6

Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans.

Tamura A, Miyawaki I, Yamada T, Kimura J, Funabashi H. Tamura A, et al. Among authors: miyawaki i. Toxicol Appl Pharmacol. 2013 Aug 15;271(1):30-40. doi: 10.1016/j.taap.2013.04.022. Epub 2013 May 5. Toxicol Appl Pharmacol. 2013. PMID: 23651737

7

Establishment of a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish.

Koseki N, Deguchi J, Yamashita A, Miyawaki I, Funabashi H. Koseki N, et al. Among authors: miyawaki i. J Toxicol Sci. 2014 Aug;39(4):579-600. doi: 10.2131/jts.39.579. J Toxicol Sci. 2014. PMID: 25056783 Free article.

8

Changes in plasma concentrations of corticosterone and its precursors after ketoconazole administration in rats: An application of simultaneous measurement of multiple steroids using LC-MS/MS.

Tochitani T, Yamashita A, Kouchi M, Fujii Y, Matsumoto I, Miyawaki I, Yamada T, Funabashi H. Tochitani T, et al. Among authors: miyawaki i. Exp Toxicol Pathol. 2016 Feb-Mar;68(2-3):125-31. doi: 10.1016/j.etp.2015.11.004. Epub 2015 Nov 21. Exp Toxicol Pathol. 2016. PMID: 26610754

9

Usefulness of Simultaneous Measurement of Plasma Steroids, Including Precursors, for the Evaluation of Drug Effects on Adrenal Steroidogenesis in Rats.

Tochitani T, Yamashita A, Matsumoto I, Kouchi M, Fujii Y, Miyawaki I, Yamada T, Bando K. Tochitani T, et al. Among authors: miyawaki i. Toxicol Pathol. 2017 Aug;45(6):756-763. doi: 10.1177/0192623317730416. Toxicol Pathol. 2017. PMID: 29046138

10

Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish.

Yamashita A, Deguchi J, Honda Y, Yamada T, Miyawaki I, Nishimura Y, Tanaka T. Yamashita A, et al. Among authors: miyawaki i. J Pharmacol Toxicol Methods. 2019 Mar-Apr;96:34-45. doi: 10.1016/j.vascn.2018.12.006. Epub 2018 Dec 27. J Pharmacol Toxicol Methods. 2019. PMID: 30594530

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