Vugmeyster Y - Search Results

1

Evaluation of the potential for QTc prolongation with avelumab.

Vugmeyster Y, Güzel G, Hennessy M, Loos AH, Dai H. Vugmeyster Y, et al. Cancer Chemother Pharmacol. 2019 Nov;84(5):1017-1026. doi: 10.1007/s00280-019-03925-z. Epub 2019 Sep 3. Cancer Chemother Pharmacol. 2019. PMID: 31478078 Free PMC article.

2

The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).

Vugmeyster Y, Borodovsky A, Maurice MM, Maehr R, Furman MH, Ploegh HL. Vugmeyster Y, et al. Mol Immunol. 2002 Nov;39(7-8):431-41. doi: 10.1016/s0161-5890(02)00123-2. Mol Immunol. 2002. PMID: 12413694

3

Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells.

Vugmeyster Y, Glas R, Pérarnau B, Lemonnier FA, Eisen H, Ploegh H. Vugmeyster Y, et al. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12492-7. doi: 10.1073/pnas.95.21.12492. Proc Natl Acad Sci U S A. 1998. PMID: 9770513 Free PMC article.

4

Time-Varying Clearance and Impact of Disease State on the Pharmacokinetics of Avelumab in Merkel Cell Carcinoma and Urothelial Carcinoma.

Wilkins JJ, Brockhaus B, Dai H, Vugmeyster Y, White JT, Brar S, Bello CL, Neuteboom B, Wade JR, Girard P, Khandelwal A. Wilkins JJ, et al. Among authors: vugmeyster y. CPT Pharmacometrics Syst Pharmacol. 2019 Jun;8(6):415-427. doi: 10.1002/psp4.12406. Epub 2019 Apr 25. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 30980481 Free PMC article.

5

Population Pharmacokinetic Analysis of Bintrafusp Alfa in Different Cancer Types.

Wilkins JJ, Vugmeyster Y, Dussault I, Girard P, Khandelwal A. Wilkins JJ, et al. Among authors: vugmeyster y. Adv Ther. 2019 Sep;36(9):2414-2433. doi: 10.1007/s12325-019-01018-0. Epub 2019 Jul 5. Adv Ther. 2019. PMID: 31278692

6

Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1.

Vugmeyster Y, Wilkins J, Koenig A, El Bawab S, Dussault I, Ojalvo LS, De Banerjee S, Klopp-Schulze L, Khandelwal A. Vugmeyster Y, et al. Clin Pharmacol Ther. 2020 Sep;108(3):566-574. doi: 10.1002/cpt.1776. Epub 2020 Mar 3. Clin Pharmacol Ther. 2020. PMID: 31955412 Free PMC article.

7

Characterizing Exposure-Response Relationship for Therapeutic Monoclonal Antibodies in Immuno-Oncology and Beyond: Challenges, Perspectives, and Prospects.

Dai HI, Vugmeyster Y, Mangal N. Dai HI, et al. Among authors: vugmeyster y. Clin Pharmacol Ther. 2020 Dec;108(6):1156-1170. doi: 10.1002/cpt.1953. Epub 2020 Aug 2. Clin Pharmacol Ther. 2020. PMID: 32557643 Free PMC article. Review.

8

Avelumab in paediatric patients with refractory or relapsed solid tumours: dose-escalation results from an open-label, single-arm, phase 1/2 trial.

Loeb DM, Lee JW, Morgenstern DA, Samson Y, Uyttebroeck A, Lyu CJ, Van Damme A, Nysom K, Macy ME, Zorzi AP, Xiong J, Pollert P, Joerg I, Vugmeyster Y, Ruisi M, Kang HJ. Loeb DM, et al. Among authors: vugmeyster y. Cancer Immunol Immunother. 2022 Oct;71(10):2485-2495. doi: 10.1007/s00262-022-03159-8. Epub 2022 Mar 9. Cancer Immunol Immunother. 2022. PMID: 35262780 Free PMC article. Clinical Trial.

9

Avelumab Dose Selection for Clinical Studies in Pediatric Patients with Solid Tumors.

Vugmeyster Y, Grisic AM, Brockhaus B, Rueckert P, Ruisi M, Dai H, Khandelwal A. Vugmeyster Y, et al. Clin Pharmacokinet. 2022 Jul;61(7):985-995. doi: 10.1007/s40262-022-01111-8. Epub 2022 Apr 29. Clin Pharmacokinet. 2022. PMID: 35484319 Free PMC article.

10

Model-informed approach for risk management of bleeding toxicities for bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1.

Vugmeyster Y, Grisic AM, Wilkins JJ, Loos AH, Hallwachs R, Osada M, Venkatakrishnan K, Khandelwal A. Vugmeyster Y, et al. Cancer Chemother Pharmacol. 2022 Oct;90(4):369-379. doi: 10.1007/s00280-022-04468-6. Epub 2022 Sep 6. Cancer Chemother Pharmacol. 2022. PMID: 36066618 Free PMC article.

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