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Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer.
Munkley J, Li L, Krishnan SRG, Hysenaj G, Scott E, Dalgliesh C, Oo HZ, Maia TM, Cheung K, Ehrmann I, Livermore KE, Zielinska H, Thompson O, Knight B, McCullagh P, McGrath J, Crundwell M, Harries LW, Daugaard M, Cockell S, Barbosa-Morais NL, Oltean S, Elliott DJ. Munkley J, et al. Among authors: li l. Elife. 2019 Sep 3;8:e47678. doi: 10.7554/eLife.47678. Elife. 2019. PMID: 31478829 Free PMC article.
The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor.
Legge D, Li L, Moriarty W, Lee D, Szemes M, Zahed A, Panousopoulos L, Chung WY, Aghabi Y, Barratt J, Williams R, Pritchard-Jones K, Malik KTA, Oltean S, Brown KW. Legge D, et al. Among authors: li l. Mol Oncol. 2022 Feb;16(3):630-647. doi: 10.1002/1878-0261.13101. Epub 2021 Sep 28. Mol Oncol. 2022. PMID: 34520622 Free PMC article.
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