Tao X - Search Results

1

Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity.

Zhu Y, Li C, Tao X, Brazill JM, Park J, Diaz-Perez Z, Zhai RG. Zhu Y, et al. Among authors: tao x. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19165-19175. doi: 10.1073/pnas.1904563116. Epub 2019 Sep 4. Proc Natl Acad Sci U S A. 2019. PMID: 31484760 Free PMC article.

2

MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing.

Park J, Zhu Y, Tao X, Brazill JM, Li C, Wuchty S, Zhai RG. Park J, et al. Among authors: tao x. iScience. 2019 Sep 27;19:1048-1064. doi: 10.1016/j.isci.2019.08.052. Epub 2019 Aug 30. iScience. 2019. PMID: 31522116 Free PMC article.

3

Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome.

Tantak MP, Sekhar V, Tao X, Zhai RG, Phanstiel O 4th. Tantak MP, et al. Among authors: tao x. J Med Chem. 2021 Nov 11;64(21):15593-15607. doi: 10.1021/acs.jmedchem.1c00419. Epub 2021 Oct 25. J Med Chem. 2021. PMID: 34695351 Free PMC article.

4

NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis.

Liu J, Tao X, Zhu Y, Li C, Ruan K, Diaz-Perez Z, Rai P, Wang H, Zhai RG. Liu J, et al. Among authors: tao x. Elife. 2021 Dec 17;10:e70046. doi: 10.7554/eLife.70046. Elife. 2021. PMID: 34919052 Free PMC article.

5

Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells.

Tao X, Zhu Y, Diaz-Perez Z, Yu SH, Foley JR, Stewart TM, Casero RA Jr, Steet R, Zhai RG. Tao X, et al. JCI Insight. 2022 Jul 8;7(13):e158457. doi: 10.1172/jci.insight.158457. JCI Insight. 2022. PMID: 35801587 Free PMC article.

6

Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy.

Tao X, Liu J, Diaz-Perez Z, Foley JR, Stewart TM, Casero RA Jr, Zhai RG. Tao X, et al. bioRxiv [Preprint]. 2023 Mar 18:2023.03.17.533015. doi: 10.1101/2023.03.17.533015. bioRxiv. 2023. PMID: 36993333 Free PMC article. Preprint.

7

Sorbitol reduction via govorestat ameliorates synaptic dysfunction and neurodegeneration in sorbitol dehydrogenase deficiency.

Zhu Y, Lobato AG, Rebelo AP, Canic T, Ortiz-Vega N, Tao X, Syed S, Yanick C, Saporta M, Shy M, Perfetti R, Shendelman S, Züchner S, Zhai RG. Zhu Y, et al. Among authors: tao x. JCI Insight. 2023 May 22;8(10):e164954. doi: 10.1172/jci.insight.164954. JCI Insight. 2023. PMID: 37014713 Free PMC article.

8

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome.

Stewart TM, Foley JR, Holbert CE, Khomutov M, Rastkari N, Tao X, Khomutov AR, Zhai RG, Casero RA Jr. Stewart TM, et al. Among authors: tao x. EMBO Mol Med. 2023 Nov 8;15(11):e17833. doi: 10.15252/emmm.202317833. Epub 2023 Sep 13. EMBO Mol Med. 2023. PMID: 37702369 Free PMC article.

9

Reduction of spermine synthase enhances autophagy to suppress Tau accumulation.

Tao X, Liu J, Diaz-Perez Z, Foley JR, Nwafor A, Stewart TM, Casero RA Jr, Zhai RG. Tao X, et al. Cell Death Dis. 2024 May 13;15(5):333. doi: 10.1038/s41419-024-06720-8. Cell Death Dis. 2024. PMID: 38740758 Free PMC article.

10

Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia.

Lobato AG, Ortiz-Vega N, Canic T, Tao X, Bucan N, Ruan K, Rebelo AP, Schule R, Zuchner S, Syed S, Zhai RG. Lobato AG, et al. Among authors: tao x. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870(7):167348. doi: 10.1016/j.bbadis.2024.167348. Epub 2024 Jul 8. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38986817 Free article.

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