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Safety and efficacy of AMG 714 in adults with coeliac disease exposed to gluten challenge: a phase 2a, randomised, double-blind, placebo-controlled study.
Lähdeaho ML, Scheinin M, Vuotikka P, Taavela J, Popp A, Laukkarinen J, Koffert J, Koivurova OP, Pesu M, Kivelä L, Lovró Z, Keisala J, Isola J, Parnes JR, Leon F, Mäki M. Lähdeaho ML, et al. Among authors: pesu m. Lancet Gastroenterol Hepatol. 2019 Dec;4(12):948-959. doi: 10.1016/S2468-1253(19)30264-X. Epub 2019 Sep 4. Lancet Gastroenterol Hepatol. 2019. PMID: 31494096 Clinical Trial.
FURIN regulates cytotoxic T-lymphocyte effector function and memory cell transition in mice.
Ojanen MJT, Caro FM, Aittomäki S, Ploquin MJ, Ortutay Z, Pekkarinen M, Kesseli J, Vähätupa M, Määttä J, Nykter M, Junttila IS, Järvinen TAH, O Shea JJ, Biron CA, Pesu M. Ojanen MJT, et al. Among authors: pesu m. Eur J Immunol. 2023 Jun;53(6):e2250246. doi: 10.1002/eji.202250246. Epub 2023 Apr 28. Eur J Immunol. 2023. PMID: 37015057 Free article.
Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).
Turpeinen H, Oksanen A, Kivinen V, Kukkurainen S, Uusimäki A, Rämet M, Parikka M, Hytönen VP, Nykter M, Pesu M. Turpeinen H, et al. Among authors: pesu m. J Biol Chem. 2013 Dec 20;288(51):36610-23. doi: 10.1074/jbc.M113.453183. Epub 2013 Oct 31. J Biol Chem. 2013. PMID: 24178295 Free PMC article.
Myeloid cell expressed proprotein convertase FURIN attenuates inflammation.
Cordova ZM, Grönholm A, Kytölä V, Taverniti V, Hämäläinen S, Aittomäki S, Niininen W, Junttila I, Ylipää A, Nykter M, Pesu M. Cordova ZM, et al. Among authors: pesu m. Oncotarget. 2016 Aug 23;7(34):54392-54404. doi: 10.18632/oncotarget.11106. Oncotarget. 2016. PMID: 27527873 Free PMC article.
65 results