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New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells.
Garcia IJP, de Oliveira GC, de Moura Valadares JM, Banfi FF, Andrade SN, Freitas TR, Dos Santos Monção Filho E, Lima Santos H, Júnior GMV, Chaves MH, de Jesus Rodrigues D, Sanchez BAM, Varotti FP, Barbosa LA. Garcia IJP, et al. Among authors: chaves mh. Steroids. 2019 Dec;152:108490. doi: 10.1016/j.steroids.2019.108490. Epub 2019 Sep 6. Steroids. 2019. PMID: 31499071
Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs.
Banfi FF, Krombauer GC, da Fonseca AL, Nunes RR, Andrade SN, de Rezende MA, Chaves MH, Monção EDS, Taranto AG, Rodrigues DJ, Vieira GM, de Castro WV, Varotti FP, Sanchez BAM. Banfi FF, et al. Among authors: chaves mh. J Venom Anim Toxins Incl Trop Dis. 2021 Jan 8;27:e20200073. doi: 10.1590/1678-9199-JVATITD-2020-0073. eCollection 2021. J Venom Anim Toxins Incl Trop Dis. 2021. PMID: 33519927 Free PMC article.
Gallic and ellagic acids: two natural immunomodulator compounds solve infection of macrophages by Leishmania major.
Alves MMM, Brito LM, Souza AC, Queiroz BCSH, de Carvalho TP, Batista JF, Oliveira JSSM, de Mendonça IL, Lira SRS, Chaves MH, Gonçalves JCR, Carneiro SMP, Arcanjo DDR, Carvalho FAA. Alves MMM, et al. Among authors: chaves mh. Naunyn Schmiedebergs Arch Pharmacol. 2017 Sep;390(9):893-903. doi: 10.1007/s00210-017-1387-y. Epub 2017 Jun 22. Naunyn Schmiedebergs Arch Pharmacol. 2017. PMID: 28643086
Marinobufagin, a molecule from poisonous frogs, causes biochemical, morphological and cell cycle changes in human neoplasms and vegetal cells.
Machado KDC, Sousa LQ, Lima DJB, Soares BM, Cavalcanti BC, Maranhão SS, Noronha JDC, Rodrigues DJ, Militão GCG, Chaves MH, Vieira-Júnior GM, Pessoa C, Moraes MO, Sousa JMCE, Melo-Cavalcante AAC, Ferreira PMP. Machado KDC, et al. Among authors: chaves mh. Toxicol Lett. 2018 Mar 15;285:121-131. doi: 10.1016/j.toxlet.2017.12.018. Epub 2017 Dec 26. Toxicol Lett. 2018. PMID: 29287997
Gastroprotective activity of Zanthoxylum rhoifolium Lam. in animal models.
Freitas FF, Fernandes HB, Piauilino CA, Pereira SS, Carvalho KI, Chaves MH, Soares PM, Miura LM, Leite JR, Oliveira RC, Oliveira FA. Freitas FF, et al. Among authors: chaves mh. J Ethnopharmacol. 2011 Sep 1;137(1):700-8. doi: 10.1016/j.jep.2011.06.026. Epub 2011 Jun 22. J Ethnopharmacol. 2011. PMID: 21723384 Free article.
72 results