Wessels U - Search Results

1

P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.

Darowski D, Jost C, Stubenrauch K, Wessels U, Benz J, Ehler A, Freimoser-Grundschober A, Brünker P, Mössner E, Umaña P, Kobold S, Klein C. Darowski D, et al. Among authors: wessels u. Protein Eng Des Sel. 2019 Dec 31;32(5):207-218. doi: 10.1093/protein/gzz027. Protein Eng Des Sel. 2019. PMID: 31504896

2

Evaluation of an immunoassay for human-specific quantitation of therapeutic antibodies in serum samples from non-human primates.

Stubenrauch K, Wessels U, Lenz H. Stubenrauch K, et al. Among authors: wessels u. J Pharm Biomed Anal. 2009 May 1;49(4):1003-8. doi: 10.1016/j.jpba.2009.01.030. Epub 2009 Feb 5. J Pharm Biomed Anal. 2009. PMID: 19250787

3

Evaluation of a biosensor immunoassay for simultaneous characterization of isotype and binding region of human anti-tocilizumab antibodies with control by surrogate standards.

Stubenrauch K, Wessels U, Vogel R, Schleypen J. Stubenrauch K, et al. Among authors: wessels u. Anal Biochem. 2009 Jul 15;390(2):189-96. doi: 10.1016/j.ab.2009.04.021. Epub 2009 Apr 18. Anal Biochem. 2009. PMID: 19379704

4

Impact of molecular processing in the hinge region of therapeutic IgG4 antibodies on disposition profiles in cynomolgus monkeys.

Stubenrauch K, Wessels U, Regula JT, Kettenberger H, Schleypen J, Kohnert U. Stubenrauch K, et al. Among authors: wessels u. Drug Metab Dispos. 2010 Jan;38(1):84-91. doi: 10.1124/dmd.109.029751. Drug Metab Dispos. 2010. PMID: 19850673

5

Evaluation of a generic immunoassay with drug tolerance to detect immune complexes in serum samples from cynomolgus monkeys after administration of human antibodies.

Stubenrauch K, Wessels U, Essig U, Vogel R, Schleypen J. Stubenrauch K, et al. Among authors: wessels u. J Pharm Biomed Anal. 2010 Jun 5;52(2):249-54. doi: 10.1016/j.jpba.2009.12.029. Epub 2010 Jan 4. J Pharm Biomed Anal. 2010. PMID: 20083366

6

Subset analysis of patients experiencing clinical events of a potentially immunogenic nature in the pivotal clinical trials of tocilizumab for rheumatoid arthritis: Evaluation of an antidrug antibody ELISA using clinical adverse event-driven immunogenicity testing.

Stubenrauch K, Wessels U, Birnboeck H, Ramirez F, Jahreis A, Schleypen J. Stubenrauch K, et al. Among authors: wessels u. Clin Ther. 2010 Aug;32(9):1597-609. doi: 10.1016/j.clinthera.2010.07.021. Clin Ther. 2010. PMID: 20974317

7

Characterization of murine anti-human Fab antibodies for use in an immunoassay for generic quantification of human Fab fragments in non-human serum samples including cynomolgus monkey samples.

Stubenrauch K, Wessels U, Essig U, Kowalewsky F, Vogel R, Heinrich J. Stubenrauch K, et al. Among authors: wessels u. J Pharm Biomed Anal. 2013 Jan;72:208-15. doi: 10.1016/j.jpba.2012.08.023. Epub 2012 Sep 7. J Pharm Biomed Anal. 2013. PMID: 23017233

8

An immunodepletion procedure advances free angiopoietin-2 determination in human plasma samples during anti-cancer therapy with bispecific anti-Ang2/VEGF CrossMab.

Stubenrauch K, Wessels U, Essig U, Vogel R, Waltenberger H, Hansbauer A, Koehler A, Heinrich J. Stubenrauch K, et al. Among authors: wessels u. J Pharm Biomed Anal. 2015 Jan;102:459-67. doi: 10.1016/j.jpba.2014.10.005. Epub 2014 Oct 14. J Pharm Biomed Anal. 2015. PMID: 25459946

9

Detection of antidrug antibodies against human therapeutic antibodies lacking Fc-effector functions by usage of soluble Fcγ receptor I.

Wessels U, Poehler A, Moheysen-Zadeh M, Zadak M, Staack RF, Umana P, Heinrich J, Stubenrauch K. Wessels U, et al. Bioanalysis. 2016 Oct;8(20):2135-45. doi: 10.4155/bio-2016-0182. Epub 2016 Sep 1. Bioanalysis. 2016. PMID: 27582032 Free article.

10

Novel drug and soluble target tolerant antidrug antibody assay for therapeutic antibodies bearing the P329G mutation.

Wessels U, Schick E, Ritter M, Kowalewsky F, Heinrich J, Stubenrauch K. Wessels U, et al. Bioanalysis. 2017 Jun;9(11):849-859. doi: 10.4155/bio-2017-0048. Epub 2017 May 18. Bioanalysis. 2017. PMID: 28517957 Free article.

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