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Page 1
The molecular basis of chaperone-mediated interleukin 23 assembly control.
Meier S, Bohnacker S, Klose CJ, Lopez A, Choe CA, Schmid PWN, Bloemeke N, Rührnößl F, Haslbeck M, Bieren JE, Sattler M, Huang PS, Feige MJ. Meier S, et al. Among authors: huang ps. Nat Commun. 2019 Sep 11;10(1):4121. doi: 10.1038/s41467-019-12006-x. Nat Commun. 2019. PMID: 31511508 Free PMC article.
The coming of age of de novo protein design.
Huang PS, Boyken SE, Baker D. Huang PS, et al. Nature. 2016 Sep 15;537(7620):320-7. doi: 10.1038/nature19946. Nature. 2016. PMID: 27629638 Review.
De novo design of a fluorescence-activating β-barrel.
Dou J, Vorobieva AA, Sheffler W, Doyle LA, Park H, Bick MJ, Mao B, Foight GW, Lee MY, Gagnon LA, Carter L, Sankaran B, Ovchinnikov S, Marcos E, Huang PS, Vaughan JC, Stoddard BL, Baker D. Dou J, et al. Among authors: huang ps. Nature. 2018 Sep;561(7724):485-491. doi: 10.1038/s41586-018-0509-0. Epub 2018 Sep 12. Nature. 2018. PMID: 30209393 Free PMC article.
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Wayment-Steele HK, Kim DS, Choe CA, Nicol JJ, Wellington-Oguri R, Watkins AM, Parra Sperberg RA, Huang PS, Participants E, Das R. Wayment-Steele HK, et al. Among authors: huang ps. Nucleic Acids Res. 2021 Oct 11;49(18):10604-10617. doi: 10.1093/nar/gkab764. Nucleic Acids Res. 2021. PMID: 34520542 Free PMC article.
Chimeric mutants of staphylococcal hemolysin, which act as both one-component and two-component hemolysin, created by grafting the stem domain.
Ghanem N, Kanagami N, Matsui T, Takeda K, Kaneko J, Shiraishi Y, Choe CA, Uchikubo-Kamo T, Shirouzu M, Hashimoto T, Ogawa T, Matsuura T, Huang PS, Yokoyama T, Tanaka Y. Ghanem N, et al. Among authors: huang ps. FEBS J. 2022 Jun;289(12):3505-3520. doi: 10.1111/febs.16354. Epub 2022 Feb 16. FEBS J. 2022. PMID: 35030303 Free article.
Targeting peptide antigens using a multiallelic MHC I-binding system.
Du H, Mallik L, Hwang D, Sun Y, Kaku C, Hoces D, Sun SM, Ghinnagow R, Carro SD, Phan HAT, Gupta S, Blackson W, Lee H, Choe CA, Dersh D, Liu J, Bell B, Yang H, Papadaki GF, Young MC, Zhou E, El Nesr G, Goli KD, Eisenlohr LC, Minn AJ, Hernandez-Lopez RA, Jardine JG, Sgourakis NG, Huang PS. Du H, et al. Among authors: huang ps. Nat Biotechnol. 2024 Dec 13. doi: 10.1038/s41587-024-02505-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 39672954
Exploring the repeat protein universe through computational protein design.
Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Brunette TJ, et al. Among authors: huang ps. Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16. Nature. 2015. PMID: 26675729 Free PMC article.
Computational design of transmembrane pores.
Xu C, Lu P, Gamal El-Din TM, Pei XY, Johnson MC, Uyeda A, Bick MJ, Xu Q, Jiang D, Bai H, Reggiano G, Hsia Y, Brunette TJ, Dou J, Ma D, Lynch EM, Boyken SE, Huang PS, Stewart L, DiMaio F, Kollman JM, Luisi BF, Matsuura T, Catterall WA, Baker D. Xu C, et al. Among authors: huang ps. Nature. 2020 Sep;585(7823):129-134. doi: 10.1038/s41586-020-2646-5. Epub 2020 Aug 26. Nature. 2020. PMID: 32848250 Free PMC article.
253 results