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Investigation of Novel Primary and Secondary Pharmacophores and 3-Substitution in the Linking Chain of a Series of Highly Selective and Bitopic Dopamine D3 Receptor Antagonists and Partial Agonists.
Shaik AB, Kumar V, Bonifazi A, Guerrero AM, Cemaj SL, Gadiano A, Lam J, Xi ZX, Rais R, Slusher BS, Newman AH. Shaik AB, et al. Among authors: rais r. J Med Chem. 2019 Oct 24;62(20):9061-9077. doi: 10.1021/acs.jmedchem.9b00607. Epub 2019 Oct 15. J Med Chem. 2019. PMID: 31526003 Free PMC article.
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice.
Rais R, Thomas AG, Wozniak K, Wu Y, Jaaro-Peled H, Sawa A, Strick CA, Engle SJ, Brandon NJ, Rojas C, Slusher BS, Tsukamoto T. Rais R, et al. Drug Metab Dispos. 2012 Nov;40(11):2067-73. doi: 10.1124/dmd.112.046482. Epub 2012 Jul 26. Drug Metab Dispos. 2012. PMID: 22837388 Free PMC article.
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.
Shukla K, Ferraris DV, Thomas AG, Stathis M, Duvall B, Delahanty G, Alt J, Rais R, Rojas C, Gao P, Xiang Y, Dang CV, Slusher BS, Tsukamoto T. Shukla K, et al. Among authors: rais r. J Med Chem. 2012 Dec 13;55(23):10551-63. doi: 10.1021/jm301191p. Epub 2012 Nov 30. J Med Chem. 2012. PMID: 23151085 Free PMC article.
Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.
Rahn KA, Watkins CC, Alt J, Rais R, Stathis M, Grishkan I, Crainiceau CM, Pomper MG, Rojas C, Pletnikov MV, Calabresi PA, Brandt J, Barker PB, Slusher BS, Kaplin AI. Rahn KA, et al. Among authors: rais r. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20101-6. doi: 10.1073/pnas.1209934109. Epub 2012 Nov 19. Proc Natl Acad Sci U S A. 2012. PMID: 23169655 Free PMC article.
175 results