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Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies.
Appleman LJ, Beumer JH, Jiang Y, Lin Y, Ding F, Puhalla S, Swartz L, Owonikoko TK, Donald Harvey R, Stoller R, Petro DP, Tawbi HA, Argiris A, Strychor S, Pouquet M, Kiesel B, Chen AP, Gandara D, Belani CP, Chu E, Ramalingam SS. Appleman LJ, et al. Among authors: beumer jh. Cancer Chemother Pharmacol. 2019 Dec;84(6):1289-1301. doi: 10.1007/s00280-019-03960-w. Epub 2019 Sep 23. Cancer Chemother Pharmacol. 2019. PMID: 31549216 Free PMC article. Clinical Trial.
A liquid chromatography-electrospray ionization tandem mass spectrometric assay for quantitation of the histone deacetylase inhibitor, vorinostat (suberoylanilide hydroxamicacid, SAHA), and its metabolites in human serum.
Parise RA, Holleran JL, Beumer JH, Ramalingam S, Egorin MJ. Parise RA, et al. Among authors: beumer jh. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Aug 18;840(2):108-15. doi: 10.1016/j.jchromb.2006.04.044. Epub 2006 May 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2006. PMID: 16725386
Effect of antacid on imatinib absorption.
Sparano BA, Egorin MJ, Parise RA, Walters J, Komazec KA, Redner RL, Beumer JH. Sparano BA, et al. Among authors: beumer jh. Cancer Chemother Pharmacol. 2009 Feb;63(3):525-8. doi: 10.1007/s00280-008-0778-7. Epub 2008 May 24. Cancer Chemother Pharmacol. 2009. PMID: 18500518 Free PMC article. Clinical Trial.
Liquid chromatography-mass spectrometric assay for the quantitation in human plasma of ABT-888, an orally available, small molecule inhibitor of poly(ADP-ribose) polymerase.
Parise RA, Shawaqfeh M, Egorin MJ, Beumer JH. Parise RA, et al. Among authors: beumer jh. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 1;872(1-2):141-7. doi: 10.1016/j.jchromb.2008.07.032. Epub 2008 Jul 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2008. PMID: 18692448 Free PMC article.
Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma.
Reardon DA, Egorin MJ, Desjardins A, Vredenburgh JJ, Beumer JH, Lagattuta TF, Gururangan S, Herndon JE 2nd, Salvado AJ, Friedman HS. Reardon DA, et al. Among authors: beumer jh. Cancer. 2009 May 15;115(10):2188-98. doi: 10.1002/cncr.24213. Cancer. 2009. PMID: 19248046 Free PMC article. Clinical Trial.
Plasma pharmacokinetics and oral bioavailability of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU), in mice.
Beumer JH, Eiseman JL, Gilbert JA, Holleran JL, Yellow-Duke AE, Clausen DM, D'Argenio DZ, Ames MM, Hershberger PA, Parise RA, Bai L, Covey JM, Egorin MJ. Beumer JH, et al. Cancer Chemother Pharmacol. 2011 Feb;67(2):421-30. doi: 10.1007/s00280-010-1337-6. Epub 2010 May 5. Cancer Chemother Pharmacol. 2011. PMID: 20443002 Free PMC article.
208 results