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The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.
Angus L, Smid M, Wilting SM, van Riet J, Van Hoeck A, Nguyen L, Nik-Zainal S, Steenbruggen TG, Tjan-Heijnen VCG, Labots M, van Riel JMGH, Bloemendal HJ, Steeghs N, Lolkema MP, Voest EE, van de Werken HJG, Jager A, Cuppen E, Sleijfer S, Martens JWM. Angus L, et al. Among authors: bloemendal hj. Nat Genet. 2019 Oct;51(10):1450-1458. doi: 10.1038/s41588-019-0507-7. Epub 2019 Sep 30. Nat Genet. 2019. PMID: 31570896 Free PMC article.
New strategies in anti-vascular cancer therapy.
Bloemendal HJ, Logtenberg T, Voest EE. Bloemendal HJ, et al. Eur J Clin Invest. 1999 Sep;29(9):802-9. doi: 10.1046/j.1365-2362.1999.00534.x. Eur J Clin Invest. 1999. PMID: 10469169 Review.
Activated vitronectin as a target for anticancer therapy with human antibodies.
Bloemendal HJ, de Boer HC, Koop EA, van Dongen AJ, Goldschmeding R, Landman WJ, Logtenberg T, Gebbink MF, Voest EE. Bloemendal HJ, et al. Cancer Immunol Immunother. 2004 Sep;53(9):799-808. doi: 10.1007/s00262-004-0506-z. Epub 2004 Jun 10. Cancer Immunol Immunother. 2004. PMID: 15197494 Free PMC article.
Imatinib treatment of poor prognosis mesenchymal-type primary colon cancer: a proof-of-concept study in the preoperative window period (ImPACCT).
Ubink I, Bloemendal HJ, Elias SG, Brink MA, Schwartz MP, Holierhoek YCW, Verheijen PM, Boerman AW, Mathijssen RHJ, de Leng WWJ, de Weger RA, van Grevenstein WMU, Koopman M, Lolkema MP, Kranenburg O, Borel Rinkes IHM. Ubink I, et al. Among authors: bloemendal hj. BMC Cancer. 2017 Apr 19;17(1):282. doi: 10.1186/s12885-017-3264-y. BMC Cancer. 2017. PMID: 28424071 Free PMC article.
Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids.
van der Velden DL, Cirkel GA, Houthuijzen JM, van Werkhoven E, Roodhart JML, Daenen LGM, Kaing S, Gerrits J, Verhoeven-Duif NM, Grootscholten C, Boot H, Sessa C, Bloemendal HJ, De Vos FY, Voest EE. van der Velden DL, et al. Among authors: bloemendal hj. Cancer Chemother Pharmacol. 2018 May;81(5):911-921. doi: 10.1007/s00280-018-3563-2. Epub 2018 Mar 24. Cancer Chemother Pharmacol. 2018. PMID: 29574584 Clinical Trial.
Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.
Ooft SN, Weeber F, Dijkstra KK, McLean CM, Kaing S, van Werkhoven E, Schipper L, Hoes L, Vis DJ, van de Haar J, Prevoo W, Snaebjornsson P, van der Velden D, Klein M, Chalabi M, Boot H, van Leerdam M, Bloemendal HJ, Beerepoot LV, Wessels L, Cuppen E, Clevers H, Voest EE. Ooft SN, et al. Among authors: bloemendal hj. Sci Transl Med. 2019 Oct 9;11(513):eaay2574. doi: 10.1126/scitranslmed.aay2574. Sci Transl Med. 2019. PMID: 31597751
Pan-cancer whole-genome analyses of metastatic solid tumours.
Priestley P, Baber J, Lolkema MP, Steeghs N, de Bruijn E, Shale C, Duyvesteyn K, Haidari S, van Hoeck A, Onstenk W, Roepman P, Voda M, Bloemendal HJ, Tjan-Heijnen VCG, van Herpen CML, Labots M, Witteveen PO, Smit EF, Sleijfer S, Voest EE, Cuppen E. Priestley P, et al. Among authors: bloemendal hj. Nature. 2019 Nov;575(7781):210-216. doi: 10.1038/s41586-019-1689-y. Epub 2019 Oct 23. Nature. 2019. PMID: 31645765 Free PMC article.
Prospective experimental treatment of colorectal cancer patients based on organoid drug responses.
Ooft SN, Weeber F, Schipper L, Dijkstra KK, McLean CM, Kaing S, van de Haar J, Prevoo W, van Werkhoven E, Snaebjornsson P, Hoes LR, Chalabi M, van der Velden D, van Leerdam M, Boot H, Grootscholten C, Huitema ADR, Bloemendal HJ, Cuppen E, Voest EE. Ooft SN, et al. Among authors: bloemendal hj. ESMO Open. 2021 Jun;6(3):100103. doi: 10.1016/j.esmoop.2021.100103. Epub 2021 Apr 19. ESMO Open. 2021. PMID: 33887686 Free PMC article.
Harmonising patient-access programmes: the Dutch DRUG Access Protocol platform.
Zeverijn LJ, van Waalwijk van Doorn-Khosrovani SB, van Roy AAMGP, Timmers L, Ly Tran TH, de Boer JE, de Wit GF, Geurts BS, Gelderblom H, Verheul HMW, Blijlevens N, Wymenga ANM, Eskens FALM, Smit EF, Bloemendal HJ, Voest EE. Zeverijn LJ, et al. Among authors: bloemendal hj. Lancet Oncol. 2022 Feb;23(2):198-201. doi: 10.1016/S1470-2045(21)00707-5. Lancet Oncol. 2022. PMID: 35114116 No abstract available.
Consensus molecular subtype 4 (CMS4)-targeted therapy in primary colon cancer: A proof-of-concept study.
Peters NA, Constantinides A, Ubink I, van Kuik J, Bloemendal HJ, van Dodewaard JM, Brink MA, Schwartz TP, Lolkema MPJK, Lacle MM, Moons LM, Geesing J, van Grevenstein WMU, Roodhart JML, Koopman M, Elias SG, Borel Rinkes IHM, Kranenburg O. Peters NA, et al. Among authors: bloemendal hj. Front Oncol. 2022 Sep 6;12:969855. doi: 10.3389/fonc.2022.969855. eCollection 2022. Front Oncol. 2022. PMID: 36147916 Free PMC article.
70 results