Lolkema MP - Search Results

1

The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.

Angus L, Smid M, Wilting SM, van Riet J, Van Hoeck A, Nguyen L, Nik-Zainal S, Steenbruggen TG, Tjan-Heijnen VCG, Labots M, van Riel JMGH, Bloemendal HJ, Steeghs N, Lolkema MP, Voest EE, van de Werken HJG, Jager A, Cuppen E, Sleijfer S, Martens JWM. Angus L, et al. Among authors: lolkema mp. Nat Genet. 2019 Oct;51(10):1450-1458. doi: 10.1038/s41588-019-0507-7. Epub 2019 Sep 30. Nat Genet. 2019. PMID: 31570896 Free PMC article.

2

A phase I study of ATR inhibitor gartisertib (M4344) as a single agent and in combination with carboplatin in patients with advanced solid tumours.

Burris HA, Berlin J, Arkenau T, Cote GM, Lolkema MP, Ferrer-Playan J, Kalapur A, Bolleddula J, Locatelli G, Goddemeier T, Gounaris I, de Bono J. Burris HA, et al. Among authors: lolkema mp. Br J Cancer. 2024 Apr;130(7):1131-1140. doi: 10.1038/s41416-023-02436-2. Epub 2024 Jan 29. Br J Cancer. 2024. PMID: 38287179 Free PMC article. Clinical Trial.

3

The von Hippel-Lindau tumor suppressor protein influences microtubule dynamics at the cell periphery.

Lolkema MP, Mehra N, Jorna AS, van Beest M, Giles RH, Voest EE. Lolkema MP, et al. Exp Cell Res. 2004 Dec 10;301(2):139-46. doi: 10.1016/j.yexcr.2004.07.016. Exp Cell Res. 2004. PMID: 15530850

4

Tumor suppression by the von Hippel-Lindau protein requires phosphorylation of the acidic domain.

Lolkema MP, Gervais ML, Snijckers CM, Hill RP, Giles RH, Voest EE, Ohh M. Lolkema MP, et al. J Biol Chem. 2005 Jun 10;280(23):22205-11. doi: 10.1074/jbc.M503220200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15824109 Free article.

5

The von Hippel-Lindau tumour suppressor interacts with microtubules through kinesin-2.

Lolkema MP, Mans DA, Snijckers CM, van Noort M, van Beest M, Voest EE, Giles RH. Lolkema MP, et al. FEBS Lett. 2007 Oct 2;581(24):4571-6. doi: 10.1016/j.febslet.2007.08.050. Epub 2007 Aug 31. FEBS Lett. 2007. PMID: 17825299 Free article.

6

Allele-specific regulation of primary cilia function by the von Hippel-Lindau tumor suppressor.

Lolkema MP, Mans DA, Ulfman LH, Volpi S, Voest EE, Giles RH. Lolkema MP, et al. Eur J Hum Genet. 2008 Jan;16(1):73-8. doi: 10.1038/sj.ejhg.5201930. Epub 2007 Oct 3. Eur J Hum Genet. 2008. PMID: 17912253

7

Mobility of the von Hippel-Lindau tumour suppressor protein is regulated by kinesin-2.

Mans DA, Lolkema MP, van Beest M, Daenen LG, Voest EE, Giles RH. Mans DA, et al. Among authors: lolkema mp. Exp Cell Res. 2008 Apr 1;314(6):1229-36. doi: 10.1016/j.yexcr.2007.12.020. Epub 2008 Jan 5. Exp Cell Res. 2008. PMID: 18261724

8

Late release of circulating endothelial cells and endothelial progenitor cells after chemotherapy predicts response and survival in cancer patients.

Roodhart JM, Langenberg MH, Vermaat JS, Lolkema MP, Baars A, Giles RH, Witteveen EO, Voest EE. Roodhart JM, et al. Among authors: lolkema mp. Neoplasia. 2010 Jan;12(1):87-94. doi: 10.1593/neo.91460. Neoplasia. 2010. PMID: 20072657 Free PMC article.

9

Genetic analysis of von Hippel-Lindau disease.

Nordstrom-O'Brien M, van der Luijt RB, van Rooijen E, van den Ouweland AM, Majoor-Krakauer DF, Lolkema MP, van Brussel A, Voest EE, Giles RH. Nordstrom-O'Brien M, et al. Among authors: lolkema mp. Hum Mutat. 2010 May;31(5):521-37. doi: 10.1002/humu.21219. Hum Mutat. 2010. PMID: 20151405

10

Ethical, legal, and counseling challenges surrounding the return of genetic results in oncology.

Lolkema MP, Gadellaa-van Hooijdonk CG, Bredenoord AL, Kapitein P, Roach N, Cuppen E, Knoers NV, Voest EE. Lolkema MP, et al. J Clin Oncol. 2013 May 20;31(15):1842-8. doi: 10.1200/JCO.2012.45.2789. Epub 2013 Apr 15. J Clin Oncol. 2013. PMID: 23589552 Review.

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