Li K - Search Results

1

Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.

Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ. Park E, et al. Among authors: li k. Nature. 2019 Nov;575(7783):545-550. doi: 10.1038/s41586-019-1660-y. Epub 2019 Oct 3. Nature. 2019. PMID: 31581174 Free PMC article.

2

Discovery and Structural Characterization of ATP-Site Ligands for the Wild-Type and V617F Mutant JAK2 Pseudokinase Domain.

McNally R, Li Q, Li K, Dekker C, Vangrevelinghe E, Jones M, Chène P, Machauer R, Radimerski T, Eck MJ. McNally R, et al. Among authors: li k, li q. ACS Chem Biol. 2019 Apr 19;14(4):587-593. doi: 10.1021/acschembio.8b00722. Epub 2019 Mar 11. ACS Chem Biol. 2019. PMID: 30763067

3

The protein kinase Akt acts as a coat adaptor in endocytic recycling.

Hsu JW, Bai M, Li K, Yang JS, Chu N, Cole PA, Eck MJ, Li J, Hsu VW. Hsu JW, et al. Among authors: li j, li k. Nat Cell Biol. 2020 Aug;22(8):927-933. doi: 10.1038/s41556-020-0530-z. Epub 2020 Jun 15. Nat Cell Biol. 2020. PMID: 32541877 Free PMC article.

4

Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.

Nakamura IT, Kohsaka S, Ikegami M, Ikeuchi H, Ueno T, Li K, Beyett TS, Koyama T, Shimizu T, Yamamoto N, Takahashi F, Takahashi K, Eck MJ, Mano H. Nakamura IT, et al. Among authors: li k. NPJ Precis Oncol. 2021 Jul 16;5(1):66. doi: 10.1038/s41698-021-00204-0. NPJ Precis Oncol. 2021. PMID: 34272467 Free PMC article.

5

Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation.

Gonzalez-Del Pino GL, Li K, Park E, Schmoker AM, Ha BH, Eck MJ. Gonzalez-Del Pino GL, et al. Among authors: li k. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2107207118. doi: 10.1073/pnas.2107207118. Proc Natl Acad Sci U S A. 2021. PMID: 34470822 Free PMC article.

6

Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib.

Tkacik E, Li K, Gonzalez-Del Pino G, Ha BH, Vinals J, Park E, Beyett TS, Eck MJ. Tkacik E, et al. Among authors: li k. J Biol Chem. 2023 May;299(5):104634. doi: 10.1016/j.jbc.2023.104634. Epub 2023 Mar 22. J Biol Chem. 2023. PMID: 36963492 Free PMC article.

7

Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides.

Tokareva OS, Li K, Travaline TL, Thomson TM, Swiecicki JM, Moussa M, Ramirez JD, Litchman S, Verdine GL, McGee JH. Tokareva OS, et al. Among authors: li k. Nat Commun. 2023 Nov 1;14(1):6992. doi: 10.1038/s41467-023-42395-z. Nat Commun. 2023. PMID: 37914719 Free PMC article.

8

Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase.

Li K, Fielding EN, Condurso HL, Bruner SD. Li K, et al. Acta Crystallogr D Struct Biol. 2017 Jul 1;73(Pt 7):573-580. doi: 10.1107/S2059798317007045. Epub 2017 Jun 30. Acta Crystallogr D Struct Biol. 2017. PMID: 28695857

9

Structural basis for precursor protein-directed ribosomal peptide macrocyclization.

Li K, Condurso HL, Li G, Ding Y, Bruner SD. Li K, et al. Among authors: li g. Nat Chem Biol. 2016 Nov;12(11):973-979. doi: 10.1038/nchembio.2200. Epub 2016 Sep 26. Nat Chem Biol. 2016. PMID: 27669417 Free PMC article.

10

A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate.

Zhang Y, Li K, Yang G, McBride JL, Bruner SD, Ding Y. Zhang Y, et al. Among authors: li k. Nat Commun. 2018 May 3;9(1):1780. doi: 10.1038/s41467-018-04154-3. Nat Commun. 2018. PMID: 29725007 Free PMC article.

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