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Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.
Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B. Bender M, et al. Among authors: heinze kg. Nat Commun. 2014 Sep 4;5:4746. doi: 10.1038/ncomms5746. Nat Commun. 2014. PMID: 25187265 Free article.
Corrigendum: Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect.
Bender M, Stritt S, Nurden P, van Eeuwijk JM, Zieger B, Kentouche K, Schulze H, Morbach H, Stegner D, Heinze KG, Dütting S, Gupta S, Witke W, Falet H, Fischer A, Hartwig JH, Nieswandt B. Bender M, et al. Among authors: heinze kg. Nat Commun. 2015 Mar 6;6:6507. doi: 10.1038/ncomms7507. Nat Commun. 2015. PMID: 25744693 Free PMC article. No abstract available.
A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis.
Dütting S, Gaits-Iacovoni F, Stegner D, Popp M, Antkowiak A, van Eeuwijk JMM, Nurden P, Stritt S, Heib T, Aurbach K, Angay O, Cherpokova D, Heinz N, Baig AA, Gorelashvili MG, Gerner F, Heinze KG, Ware J, Krohne G, Ruggeri ZM, Nurden AT, Schulze H, Modlich U, Pleines I, Brakebusch C, Nieswandt B. Dütting S, et al. Among authors: heinze kg. Nat Commun. 2017 Jun 15;8:15838. doi: 10.1038/ncomms15838. Nat Commun. 2017. PMID: 28643773 Free PMC article.
Twinfilin 2a regulates platelet reactivity and turnover in mice.
Stritt S, Beck S, Becker IC, Vögtle T, Hakala M, Heinze KG, Du X, Bender M, Braun A, Lappalainen P, Nieswandt B. Stritt S, et al. Among authors: heinze kg. Blood. 2017 Oct 12;130(15):1746-1756. doi: 10.1182/blood-2017-02-770768. Epub 2017 Jul 25. Blood. 2017. PMID: 28743718 Free article.
Thrombopoiesis is spatially regulated by the bone marrow vasculature.
Stegner D, vanEeuwijk JMM, Angay O, Gorelashvili MG, Semeniak D, Pinnecker J, Schmithausen P, Meyer I, Friedrich M, Dütting S, Brede C, Beilhack A, Schulze H, Nieswandt B, Heinze KG. Stegner D, et al. Among authors: heinze kg. Nat Commun. 2017 Jul 25;8(1):127. doi: 10.1038/s41467-017-00201-7. Nat Commun. 2017. PMID: 28743899 Free PMC article.
BIN2 orchestrates platelet calcium signaling in thrombosis and thrombo-inflammation.
Volz J, Kusch C, Beck S, Popp M, Vögtle T, Meub M, Scheller I, Heil HS, Preu J, Schuhmann MK, Hemmen K, Premsler T, Sickmann A, Heinze KG, Stegner D, Stoll G, Braun A, Sauer M, Nieswandt B. Volz J, et al. Among authors: heinze kg. J Clin Invest. 2020 Nov 2;130(11):6064-6079. doi: 10.1172/JCI136457. J Clin Invest. 2020. PMID: 32750041 Free PMC article.
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