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Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity.
Quambusch L, Landel I, Depta L, Weisner J, Uhlenbrock N, Müller MP, Glanemann F, Althoff K, Siveke JT, Rauh D. Quambusch L, et al. Among authors: rauh d. Angew Chem Int Ed Engl. 2019 Dec 19;58(52):18823-18829. doi: 10.1002/anie.201909857. Epub 2019 Nov 8. Angew Chem Int Ed Engl. 2019. PMID: 31584233 Free PMC article.
A new screening assay for allosteric inhibitors of cSrc.
Simard JR, Klüter S, Grütter C, Getlik M, Rabiller M, Rode HB, Rauh D. Simard JR, et al. Among authors: rauh d. Nat Chem Biol. 2009 Jun;5(6):394-6. doi: 10.1038/nchembio.162. Epub 2009 Apr 26. Nat Chem Biol. 2009. PMID: 19396179
A scaffold-tree-merging strategy for prospective bioactivity annotation of gamma-pyrones.
Wetzel S, Wilk W, Chammaa S, Sperl B, Roth AG, Yektaoglu A, Renner S, Berg T, Arenz C, Giannis A, Oprea TI, Rauh D, Kaiser M, Waldmann H. Wetzel S, et al. Among authors: rauh d. Angew Chem Int Ed Engl. 2010 May 10;49(21):3666-70. doi: 10.1002/anie.200906555. Angew Chem Int Ed Engl. 2010. PMID: 20394088 No abstract available.
Selective detection of allosteric phosphatase inhibitors.
Schneider R, Beumer C, Simard JR, Grütter C, Rauh D. Schneider R, et al. Among authors: rauh d. J Am Chem Soc. 2013 May 8;135(18):6838-41. doi: 10.1021/ja4030484. Epub 2013 Apr 26. J Am Chem Soc. 2013. PMID: 23611635
178 results