Clevers H - Search Results

1

Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids.

Dekkers JF, Whittle JR, Vaillant F, Chen HR, Dawson C, Liu K, Geurts MH, Herold MJ, Clevers H, Lindeman GJ, Visvader JE. Dekkers JF, et al. Among authors: clevers h. J Natl Cancer Inst. 2020 May 1;112(5):540-544. doi: 10.1093/jnci/djz196. J Natl Cancer Inst. 2020. PMID: 31589320 Free PMC article.

2

Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling.

van de Wetering M, Barker N, Harkes IC, van der Heyden M, Dijk NJ, Hollestelle A, Klijn JG, Clevers H, Schutte M. van de Wetering M, et al. Among authors: clevers h. Cancer Res. 2001 Jan 1;61(1):278-84. Cancer Res. 2001. PMID: 11196175

3

A functional CFTR assay using primary cystic fibrosis intestinal organoids.

Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. Dekkers JF, et al. Among authors: clevers h. Nat Med. 2013 Jul;19(7):939-45. doi: 10.1038/nm.3201. Epub 2013 Jun 2. Nat Med. 2013. PMID: 23727931

4

Generation of L cells in mouse and human small intestine organoids.

Petersen N, Reimann F, Bartfeld S, Farin HF, Ringnalda FC, Vries RG, van den Brink S, Clevers H, Gribble FM, de Koning EJ. Petersen N, et al. Among authors: clevers h. Diabetes. 2014 Feb;63(2):410-20. doi: 10.2337/db13-0991. Epub 2013 Oct 15. Diabetes. 2014. PMID: 24130334 Free PMC article.

5

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.

Schwank G, Koo BK, Sasselli V, Dekkers JF, Heo I, Demircan T, Sasaki N, Boymans S, Cuppen E, van der Ent CK, Nieuwenhuis EE, Beekman JM, Clevers H. Schwank G, et al. Among authors: clevers h. Cell Stem Cell. 2013 Dec 5;13(6):653-8. doi: 10.1016/j.stem.2013.11.002. Cell Stem Cell. 2013. PMID: 24315439 Free article.

6

Development and application of human adult stem or progenitor cell organoids.

Rookmaaker MB, Schutgens F, Verhaar MC, Clevers H. Rookmaaker MB, et al. Among authors: clevers h. Nat Rev Nephrol. 2015 Sep;11(9):546-54. doi: 10.1038/nrneph.2015.118. Epub 2015 Jul 28. Nat Rev Nephrol. 2015. PMID: 26215513 Review.

7

Tissue-specific designs of stem cell hierarchies.

Visvader JE, Clevers H. Visvader JE, et al. Among authors: clevers h. Nat Cell Biol. 2016 Apr;18(4):349-55. doi: 10.1038/ncb3332. Epub 2016 Mar 21. Nat Cell Biol. 2016. PMID: 26999737

8

CRISPR/Cas9-Mediated Genome Editing of Mouse Small Intestinal Organoids.

Schwank G, Clevers H. Schwank G, et al. Among authors: clevers h. Methods Mol Biol. 2016;1422:3-11. doi: 10.1007/978-1-4939-3603-8_1. Methods Mol Biol. 2016. PMID: 27246017

9

Modeling Development and Disease with Organoids.

Clevers H. Clevers H. Cell. 2016 Jun 16;165(7):1586-1597. doi: 10.1016/j.cell.2016.05.082. Cell. 2016. PMID: 27315476 Free article. Review.

10

Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.

Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM. Dekkers JF, et al. Among authors: clevers h. Sci Transl Med. 2016 Jun 22;8(344):344ra84. doi: 10.1126/scitranslmed.aad8278. Sci Transl Med. 2016. PMID: 27334259

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