Shair MD - Search Results

1

High-Affinity Alkynyl Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT).

Policarpo RL, Decultot L, May E, Kuzmič P, Carlson S, Huang D, Chu V, Wright BA, Dhakshinamoorthy S, Kannt A, Rani S, Dittakavi S, Panarese JD, Gaudet R, Shair MD. Policarpo RL, et al. Among authors: shair md. J Med Chem. 2019 Nov 14;62(21):9837-9873. doi: 10.1021/acs.jmedchem.9b01238. Epub 2019 Oct 25. J Med Chem. 2019. PMID: 31589440 Free PMC article.

2

Asymmetric Total Synthesis of C9'-epi-Sinefungin.

Decultot L, Policarpo RL, Wright BA, Huang D, Shair MD. Decultot L, et al. Among authors: shair md. Org Lett. 2020 Jul 17;22(14):5594-5599. doi: 10.1021/acs.orglett.0c01956. Epub 2020 Jul 6. Org Lett. 2020. PMID: 32628491

3

Potent Uncompetitive Inhibitors of Nicotinamide N-Methyltransferase (NNMT) as In Vivo Chemical Probes.

Barrows RD, Jeffries DE, Vishe M, Tukachinsky H, Zheng SL, Li F, Ma Z, Li X, Jin S, Song H, Zhang R, Zhang S, Ni J, Luan H, Wen L, Rongshan Y, Ying C, Shair MD. Barrows RD, et al. Among authors: shair md. J Med Chem. 2022 Nov 10;65(21):14642-14654. doi: 10.1021/acs.jmedchem.2c01166. Epub 2022 Oct 26. J Med Chem. 2022. PMID: 36288465

4

Stereoselective synthesis of 2-deoxy-beta-glycosides using anomeric O-alkylation/arylation.

Morris WJ, Shair MD. Morris WJ, et al. Among authors: shair md. Org Lett. 2009 Jan 1;11(1):9-12. doi: 10.1021/ol8022006. Org Lett. 2009. PMID: 19061365 Free PMC article.

5

Gram-scale synthesis of the A'B'-subunit of angelmicin B.

Milgram BC, Liau BB, Shair MD. Milgram BC, et al. Among authors: shair md. Org Lett. 2011 Dec 16;13(24):6436-9. doi: 10.1021/ol202728v. Epub 2011 Nov 15. Org Lett. 2011. PMID: 22084899 Free PMC article.

6

Synthesis of the C4-epi-lomaiviticin B core reveals subtle stereoelectronic effects.

Lee AS, Shair MD. Lee AS, et al. Among authors: shair md. Org Lett. 2013 May 17;15(10):2390-3. doi: 10.1021/ol400832r. Epub 2013 May 9. Org Lett. 2013. PMID: 23659351

7

Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin.

Sparling BA, Tucker JK, Moebius DC, Shair MD. Sparling BA, et al. Among authors: shair md. Org Lett. 2015 Jul 17;17(14):3398-401. doi: 10.1021/acs.orglett.5b01121. Epub 2015 Jun 30. Org Lett. 2015. PMID: 26125288

8

STAT3 Inhibitory Activity of Structurally Simplified Withaferin A Analogues.

Tahara T, Streit U, Pelish HE, Shair MD. Tahara T, et al. Among authors: shair md. Org Lett. 2017 Apr 7;19(7):1538-1541. doi: 10.1021/acs.orglett.7b00332. Epub 2017 Mar 28. Org Lett. 2017. PMID: 28350459

9

Catalytic Allylic Oxidation to Generate Vinylogous Acyl Sulfonates from Vinyl Sulfonates.

Tucker JK, Shair MD. Tucker JK, et al. Among authors: shair md. Org Lett. 2019 Apr 5;21(7):2473-2476. doi: 10.1021/acs.orglett.9b00845. Epub 2019 Mar 18. Org Lett. 2019. PMID: 30883141

10

Total synthesis of (+)-fastigiatine.

Liau BB, Shair MD. Liau BB, et al. Among authors: shair md. J Am Chem Soc. 2010 Jul 21;132(28):9594-5. doi: 10.1021/ja104575h. J Am Chem Soc. 2010. PMID: 20568766

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