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Page 1
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Chen Z, Ji Z, Ngiow SF, Manne S, Cai Z, Huang AC, Johnson J, Staupe RP, Bengsch B, Xu C, Yu S, Kurachi M, Herati RS, Vella LA, Baxter AE, Wu JE, Khan O, Beltra JC, Giles JR, Stelekati E, McLane LM, Lau CW, Yang X, Berger SL, Vahedi G, Ji H, Wherry EJ. Chen Z, et al. Among authors: stelekati e. Immunity. 2019 Nov 19;51(5):840-855.e5. doi: 10.1016/j.immuni.2019.09.013. Epub 2019 Oct 9. Immunity. 2019. PMID: 31606264 Free PMC article.
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.
Bengsch B, Johnson AL, Kurachi M, Odorizzi PM, Pauken KE, Attanasio J, Stelekati E, McLane LM, Paley MA, Delgoffe GM, Wherry EJ. Bengsch B, et al. Among authors: stelekati e. Immunity. 2016 Aug 16;45(2):358-73. doi: 10.1016/j.immuni.2016.07.008. Epub 2016 Aug 2. Immunity. 2016. PMID: 27496729 Free PMC article.
miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb.
Chen Z, Stelekati E, Kurachi M, Yu S, Cai Z, Manne S, Khan O, Yang X, Wherry EJ. Chen Z, et al. Among authors: stelekati e. Cell Rep. 2017 Sep 12;20(11):2584-2597. doi: 10.1016/j.celrep.2017.08.060. Cell Rep. 2017. PMID: 28903040 Free PMC article.
Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation.
Abdel-Hakeem MS, Manne S, Beltra JC, Stelekati E, Chen Z, Nzingha K, Ali MA, Johnson JL, Giles JR, Mathew D, Greenplate AR, Vahedi G, Wherry EJ. Abdel-Hakeem MS, et al. Among authors: stelekati e. Nat Immunol. 2021 Aug;22(8):1008-1019. doi: 10.1038/s41590-021-00975-5. Epub 2021 Jul 26. Nat Immunol. 2021. PMID: 34312545 Free PMC article.
Bystander chronic infection negatively impacts development of CD8(+) T cell memory.
Stelekati E, Shin H, Doering TA, Dolfi DV, Ziegler CG, Beiting DP, Dawson L, Liboon J, Wolski D, Ali MA, Katsikis PD, Shen H, Roos DS, Haining WN, Lauer GM, Wherry EJ. Stelekati E, et al. Immunity. 2014 May 15;40(5):801-13. doi: 10.1016/j.immuni.2014.04.010. Immunity. 2014. PMID: 24837104 Free PMC article.
Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation.
Abdel-Hakeem MS, Manne S, Beltra JC, Stelekati E, Chen Z, Nzingha K, Ali MA, Johnson JL, Giles JR, Mathew D, Greenplate AR, Vahedi G, Wherry EJ. Abdel-Hakeem MS, et al. Among authors: stelekati e. Nat Immunol. 2021 Nov;22(11):1465. doi: 10.1038/s41590-021-01057-2. Nat Immunol. 2021. PMID: 34588688 No abstract available.
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection.
Stelekati E, Cai Z, Manne S, Chen Z, Beltra JC, Buchness LA, Leng X, Ristin S, Nzingha K, Ekshyyan V, Niavi C, Abdel-Hakeem MS, Ali MA, Drury S, Lau CW, Gao Z, Ban Y, Zhou SK, Ansel KM, Kurachi M, Jordan MS, Villarino AV, Ngiow SF, Wherry EJ. Stelekati E, et al. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2106083119. doi: 10.1073/pnas.2106083119. Epub 2022 Apr 21. Proc Natl Acad Sci U S A. 2022. PMID: 35446623 Free PMC article.
21 results