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Gene editing in a Myo6 semi-dominant mouse model rescues auditory function.
Xue Y, Hu X, Wang D, Li D, Li Y, Wang F, Huang M, Gu X, Xu Z, Zhou J, Wang J, Chai R, Shen J, Chen ZY, Li GL, Yang H, Li H, Zuo E, Shu Y. Xue Y, et al. Among authors: wang f, wang j, wang d. Mol Ther. 2022 Jan 5;30(1):105-118. doi: 10.1016/j.ymthe.2021.06.015. Epub 2021 Jun 24. Mol Ther. 2022. PMID: 34174443 Free PMC article.
Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates.
Zhang L, Wang H, Xun M, Tang H, Wang J, Lv J, Zhu B, Chen Y, Wang D, Hu S, Gao Z, Liu J, Chen ZY, Chen B, Li H, Shu Y. Zhang L, et al. Among authors: wang h, wang j, wang d. Mol Ther Methods Clin Dev. 2023 Nov 10;31:101154. doi: 10.1016/j.omtm.2023.101154. eCollection 2023 Dec 14. Mol Ther Methods Clin Dev. 2023. PMID: 38027066 Free PMC article.
AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial.
Lv J, Wang H, Cheng X, Chen Y, Wang D, Zhang L, Cao Q, Tang H, Hu S, Gao K, Xun M, Wang J, Wang Z, Zhu B, Cui C, Gao Z, Guo L, Yu S, Jiang L, Yin Y, Zhang J, Chen B, Wang W, Chai R, Chen ZY, Li H, Shu Y. Lv J, et al. Among authors: wang h, wang w, wang j, wang z, wang d. Lancet. 2024 May 25;403(10441):2317-2325. doi: 10.1016/S0140-6736(23)02874-X. Epub 2024 Jan 24. Lancet. 2024. PMID: 38280389 Clinical Trial.
Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results.
Wang H, Chen Y, Lv J, Cheng X, Cao Q, Wang D, Zhang L, Zhu B, Shen M, Xu C, Xun M, Wang Z, Tang H, Hu S, Cui C, Jiang L, Yin Y, Guo L, Zhou Y, Han L, Gao Z, Zhang J, Yu S, Gao K, Wang J, Chen B, Wang W, Chen ZY, Li H, Shu Y. Wang H, et al. Among authors: wang w, wang z, wang j, wang d. Nat Med. 2024 Jul;30(7):1898-1904. doi: 10.1038/s41591-024-03023-5. Epub 2024 Jun 5. Nat Med. 2024. PMID: 38839897 Free PMC article. Clinical Trial.
217,623 results
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