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Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma.
Nassar AH, Hamieh L, Gray KP, Thorner AR, Fay AP, Lasseter KD, Abou Alaiwi S, Nuzzo PV, Flippot R, Krajewski KM, Signoretti S, Choueiri TK, Kwiatkowski DJ. Nassar AH, et al. Among authors: kwiatkowski dj. Mol Cancer Ther. 2020 Feb;19(2):690-696. doi: 10.1158/1535-7163.MCT-19-0642. Epub 2019 Oct 25. Mol Cancer Ther. 2020. PMID: 31653662
Renal and liver tumors in Tsc2(+/-) mice, a model of tuberous sclerosis complex, do not respond to treatment with atorvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor.
Finlay GA, Malhowski AJ, Polizzi K, Malinowska-Kolodziej I, Kwiatkowski DJ. Finlay GA, et al. Among authors: kwiatkowski dj. Mol Cancer Ther. 2009 Jul;8(7):1799-807. doi: 10.1158/1535-7163.MCT-09-0055. Epub 2009 Jul 7. Mol Cancer Ther. 2009. PMID: 19584242 Free PMC article.
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis.
Gan B, Lim C, Chu G, Hua S, Ding Z, Collins M, Hu J, Jiang S, Fletcher-Sananikone E, Zhuang L, Chang M, Zheng H, Wang YA, Kwiatkowski DJ, Kaelin WG Jr, Signoretti S, DePinho RA. Gan B, et al. Among authors: kwiatkowski dj. Cancer Cell. 2010 Nov 16;18(5):472-84. doi: 10.1016/j.ccr.2010.10.019. Cancer Cell. 2010. PMID: 21075312 Free PMC article.
Integrative analysis of 1q23.3 copy-number gain in metastatic urothelial carcinoma.
Riester M, Werner L, Bellmunt J, Selvarajah S, Guancial EA, Weir BA, Stack EC, Park RS, O'Brien R, Schutz FA, Choueiri TK, Signoretti S, Lloreta J, Marchionni L, Gallardo E, Rojo F, Garcia DI, Chekaluk Y, Kwiatkowski DJ, Bochner BH, Hahn WC, Ligon AH, Barletta JA, Loda M, Berman DM, Kantoff PW, Michor F, Rosenberg JE. Riester M, et al. Among authors: kwiatkowski dj. Clin Cancer Res. 2014 Apr 1;20(7):1873-83. doi: 10.1158/1078-0432.CCR-13-0759. Epub 2014 Jan 31. Clin Cancer Res. 2014. PMID: 24486590 Free PMC article.
Renal cell carcinoma in tuberous sclerosis complex.
Yang P, Cornejo KM, Sadow PM, Cheng L, Wang M, Xiao Y, Jiang Z, Oliva E, Jozwiak S, Nussbaum RL, Feldman AS, Paul E, Thiele EA, Yu JJ, Henske EP, Kwiatkowski DJ, Young RH, Wu CL. Yang P, et al. Among authors: kwiatkowski dj. Am J Surg Pathol. 2014 Jul;38(7):895-909. doi: 10.1097/PAS.0000000000000237. Am J Surg Pathol. 2014. PMID: 24832166 Free PMC article.
438 results