Rohatgi R - Search Results

1

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling.

Kinnebrew M, Iverson EJ, Patel BB, Pusapati GV, Kong JH, Johnson KA, Luchetti G, Eckert KM, McDonald JG, Covey DF, Siebold C, Radhakrishnan A, Rohatgi R. Kinnebrew M, et al. Among authors: rohatgi r. Elife. 2019 Oct 30;8:e50051. doi: 10.7554/eLife.50051. Elife. 2019. PMID: 31657721 Free PMC article.

2

The ciliary membrane.

Rohatgi R, Snell WJ. Rohatgi R, et al. Curr Opin Cell Biol. 2010 Aug;22(4):541-6. doi: 10.1016/j.ceb.2010.03.010. Epub 2010 Apr 17. Curr Opin Cell Biol. 2010. PMID: 20399632 Free PMC article. Review.

3

Oxysterols are allosteric activators of the oncoprotein Smoothened.

Nachtergaele S, Mydock LK, Krishnan K, Rammohan J, Schlesinger PH, Covey DF, Rohatgi R. Nachtergaele S, et al. Among authors: rohatgi r. Nat Chem Biol. 2012 Jan 8;8(2):211-20. doi: 10.1038/nchembio.765. Nat Chem Biol. 2012. PMID: 22231273 Free PMC article.

4

A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia.

Dorn KV, Hughes CE, Rohatgi R. Dorn KV, et al. Among authors: rohatgi r. Dev Cell. 2012 Oct 16;23(4):823-35. doi: 10.1016/j.devcel.2012.07.004. Epub 2012 Sep 13. Dev Cell. 2012. PMID: 22981989 Free PMC article.

5

Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.

Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Nachtergaele S, et al. Among authors: rohatgi r. Elife. 2013 Oct 29;2:e01340. doi: 10.7554/eLife.01340. Elife. 2013. PMID: 24171105 Free PMC article.

6

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R. Niewiadomski P, et al. Among authors: rohatgi r. Cell Rep. 2014 Jan 16;6(1):168-181. doi: 10.1016/j.celrep.2013.12.003. Epub 2013 Dec 27. Cell Rep. 2014. PMID: 24373970 Free PMC article.

7

EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia.

Pusapati GV, Hughes CE, Dorn KV, Zhang D, Sugianto P, Aravind L, Rohatgi R. Pusapati GV, et al. Among authors: rohatgi r. Dev Cell. 2014 Mar 10;28(5):483-96. doi: 10.1016/j.devcel.2014.01.021. Epub 2014 Feb 27. Dev Cell. 2014. PMID: 24582806 Free PMC article.

8

Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi.

Peyrot SM, Nachtergaele S, Luchetti G, Mydock-McGrane LK, Fujiwara H, Scherrer D, Jallouk A, Schlesinger PH, Ory DS, Covey DF, Rohatgi R. Peyrot SM, et al. Among authors: rohatgi r. J Biol Chem. 2014 Apr 18;289(16):11095-11110. doi: 10.1074/jbc.M113.540351. Epub 2014 Mar 4. J Biol Chem. 2014. PMID: 24596093 Free PMC article.

9

G-protein-coupled receptors, Hedgehog signaling and primary cilia.

Mukhopadhyay S, Rohatgi R. Mukhopadhyay S, et al. Among authors: rohatgi r. Semin Cell Dev Biol. 2014 Sep;33:63-72. doi: 10.1016/j.semcdb.2014.05.002. Epub 2014 May 17. Semin Cell Dev Biol. 2014. PMID: 24845016 Free PMC article. Review.

10

Location, location, and location: compartmentalization of Hedgehog signaling at primary cilia.

Pusapati GV, Rohatgi R. Pusapati GV, et al. Among authors: rohatgi r. EMBO J. 2014 Sep 1;33(17):1852-4. doi: 10.15252/embj.201489294. Epub 2014 Jul 17. EMBO J. 2014. PMID: 25037564 Free PMC article.

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