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Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K. Brumbaugh J, et al. Among authors: charlton j. Nat Cell Biol. 2019 Nov;21(11):1449-1461. doi: 10.1038/s41556-019-0403-5. Epub 2019 Oct 28. Nat Cell Biol. 2019. PMID: 31659274 Free PMC article.
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.
Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K. Di Stefano B, et al. Among authors: charlton j. Cell Stem Cell. 2019 Nov 7;25(5):622-638.e13. doi: 10.1016/j.stem.2019.08.018. Epub 2019 Oct 3. Cell Stem Cell. 2019. PMID: 31588046 Free PMC article.
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells.
Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, Di Stefano B, Tsopoulidis N, Hoetker MS, Huebner AJ, Bar-Nur O, Almada AE, Yamamoto M, Patelunas A, Goldhamer DJ, Wagers AJ, Michor F, Meissner A, Sadreyev RI, Hochedlinger K. Yagi M, et al. Among authors: charlton j. Genes Dev. 2021 Sep 1;35(17-18):1209-1228. doi: 10.1101/gad.348678.121. Epub 2021 Aug 19. Genes Dev. 2021. PMID: 34413137 Free PMC article.
Global delay in nascent strand DNA methylation.
Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A. Charlton J, et al. Nat Struct Mol Biol. 2018 Apr;25(4):327-332. doi: 10.1038/s41594-018-0046-4. Epub 2018 Mar 12. Nat Struct Mol Biol. 2018. PMID: 29531288 Free PMC article.
Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling.
Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combémorel N, Riemenschneider C, Allègre N, Zhang J, Wajda P, Rama N, Vieugué P, Durand I, Brevet M, Gadot N, Imhof T, Merrill BJ, Koch M, Mehlen P, Chazaud C, Meissner A, Lavial F. Huyghe A, et al. Among authors: charlton j. Nat Cell Biol. 2020 Apr;22(4):389-400. doi: 10.1038/s41556-020-0483-2. Epub 2020 Mar 30. Nat Cell Biol. 2020. PMID: 32231305
Genetic determinants and epigenetic effects of pioneer-factor occupancy.
Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A. Donaghey J, et al. Among authors: charlton j. Nat Genet. 2018 Feb;50(2):250-258. doi: 10.1038/s41588-017-0034-3. Epub 2018 Jan 22. Nat Genet. 2018. PMID: 29358654 Free PMC article.
Genome-wide tracking of dCas9-methyltransferase footprints.
Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, Meissner A. Galonska C, et al. Among authors: charlton j. Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5. Nat Commun. 2018. PMID: 29426832 Free PMC article.
Targets and genomic constraints of ectopic Dnmt3b expression.
Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A. Zhang Y, et al. Among authors: charlton j. Elife. 2018 Nov 23;7:e40757. doi: 10.7554/eLife.40757. Elife. 2018. PMID: 30468428 Free PMC article.
Circadian Entrainment Triggers Maturation of Human In Vitro Islets.
Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA. Alvarez-Dominguez JR, et al. Among authors: charlton j. Cell Stem Cell. 2020 Jan 2;26(1):108-122.e10. doi: 10.1016/j.stem.2019.11.011. Epub 2019 Dec 12. Cell Stem Cell. 2020. PMID: 31839570 Free article.
594 results