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Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K. Brumbaugh J, et al. Among authors: huebner aj. Nat Cell Biol. 2019 Nov;21(11):1449-1461. doi: 10.1038/s41556-019-0403-5. Epub 2019 Oct 28. Nat Cell Biol. 2019. PMID: 31659274 Free PMC article.
Sox2 Suppresses Gastric Tumorigenesis in Mice.
Sarkar A, Huebner AJ, Sulahian R, Anselmo A, Xu X, Flattery K, Desai N, Sebastian C, Yram MA, Arnold K, Rivera M, Mostoslavsky R, Bronson R, Bass AJ, Sadreyev R, Shivdasani RA, Hochedlinger K. Sarkar A, et al. Among authors: huebner aj. Cell Rep. 2016 Aug 16;16(7):1929-41. doi: 10.1016/j.celrep.2016.07.034. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498859 Free article.
DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.
Choi J, Clement K, Huebner AJ, Webster J, Rose CM, Brumbaugh J, Walsh RM, Lee S, Savol A, Etchegaray JP, Gu H, Boyle P, Elling U, Mostoslavsky R, Sadreyev R, Park PJ, Gygi SP, Meissner A, Hochedlinger K. Choi J, et al. Among authors: huebner aj. Cell Stem Cell. 2017 May 4;20(5):706-719.e7. doi: 10.1016/j.stem.2017.03.002. Epub 2017 Mar 30. Cell Stem Cell. 2017. PMID: 28366588 Free PMC article.
Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells.
Choi J, Huebner AJ, Clement K, Walsh RM, Savol A, Lin K, Gu H, Di Stefano B, Brumbaugh J, Kim SY, Sharif J, Rose CM, Mohammad A, Odajima J, Charron J, Shioda T, Gnirke A, Gygi S, Koseki H, Sadreyev RI, Xiao A, Meissner A, Hochedlinger K. Choi J, et al. Among authors: huebner aj. Nature. 2017 Aug 10;548(7666):219-223. doi: 10.1038/nature23274. Epub 2017 Jul 26. Nature. 2017. PMID: 28746311 Free PMC article.
Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.
Bar-Nur O, Gerli MFM, Di Stefano B, Almada AE, Galvin A, Coffey A, Huebner AJ, Feige P, Verheul C, Cheung P, Payzin-Dogru D, Paisant S, Anselmo A, Sadreyev RI, Ott HC, Tajbakhsh S, Rudnicki MA, Wagers AJ, Hochedlinger K. Bar-Nur O, et al. Among authors: huebner aj. Stem Cell Reports. 2018 May 8;10(5):1505-1521. doi: 10.1016/j.stemcr.2018.04.009. Stem Cell Reports. 2018. PMID: 29742392 Free PMC article.
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.
Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, Plath K, Hochedlinger K. Di Stefano B, et al. Among authors: huebner aj. Nat Methods. 2018 Sep;15(9):732-740. doi: 10.1038/s41592-018-0104-1. Epub 2018 Aug 20. Nat Methods. 2018. PMID: 30127506 Free PMC article.
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.
Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K. Di Stefano B, et al. Among authors: huebner aj. Cell Stem Cell. 2019 Nov 7;25(5):622-638.e13. doi: 10.1016/j.stem.2019.08.018. Epub 2019 Oct 3. Cell Stem Cell. 2019. PMID: 31588046 Free PMC article.
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells.
Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, Di Stefano B, Tsopoulidis N, Hoetker MS, Huebner AJ, Bar-Nur O, Almada AE, Yamamoto M, Patelunas A, Goldhamer DJ, Wagers AJ, Michor F, Meissner A, Sadreyev RI, Hochedlinger K. Yagi M, et al. Among authors: huebner aj. Genes Dev. 2021 Sep 1;35(17-18):1209-1228. doi: 10.1101/gad.348678.121. Epub 2021 Aug 19. Genes Dev. 2021. PMID: 34413137 Free PMC article.
24 results