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Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo.
Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K. Brumbaugh J, et al. Among authors: sadreyev ri. Nat Cell Biol. 2019 Nov;21(11):1449-1461. doi: 10.1038/s41556-019-0403-5. Epub 2019 Oct 28. Nat Cell Biol. 2019. PMID: 31659274 Free PMC article.
Xist RNA is a potent suppressor of hematologic cancer in mice.
Yildirim E, Kirby JE, Brown DE, Mercier FE, Sadreyev RI, Scadden DT, Lee JT. Yildirim E, et al. Among authors: sadreyev ri. Cell. 2013 Feb 14;152(4):727-42. doi: 10.1016/j.cell.2013.01.034. Cell. 2013. PMID: 23415223 Free PMC article.
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.
Hata AN, Niederst MJ, Archibald HL, Gomez-Caraballo M, Siddiqui FM, Mulvey HE, Maruvka YE, Ji F, Bhang HE, Krishnamurthy Radhakrishna V, Siravegna G, Hu H, Raoof S, Lockerman E, Kalsy A, Lee D, Keating CL, Ruddy DA, Damon LJ, Crystal AS, Costa C, Piotrowska Z, Bardelli A, Iafrate AJ, Sadreyev RI, Stegmeier F, Getz G, Sequist LV, Faber AC, Engelman JA. Hata AN, et al. Among authors: sadreyev ri. Nat Med. 2016 Mar;22(3):262-9. doi: 10.1038/nm.4040. Epub 2016 Feb 1. Nat Med. 2016. PMID: 26828195 Free PMC article.
Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.
Nishikawa JL, Boeszoermenyi A, Vale-Silva LA, Torelli R, Posteraro B, Sohn YJ, Ji F, Gelev V, Sanglard D, Sanguinetti M, Sadreyev RI, Mukherjee G, Bhyravabhotla J, Buhrlage SJ, Gray NS, Wagner G, Näär AM, Arthanari H. Nishikawa JL, et al. Among authors: sadreyev ri. Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17. Nature. 2016. PMID: 26886795 Free PMC article.
SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b.
Kugel S, Sebastián C, Fitamant J, Ross KN, Saha SK, Jain E, Gladden A, Arora KS, Kato Y, Rivera MN, Ramaswamy S, Sadreyev RI, Goren A, Deshpande V, Bardeesy N, Mostoslavsky R. Kugel S, et al. Among authors: sadreyev ri. Cell. 2016 Jun 2;165(6):1401-1415. doi: 10.1016/j.cell.2016.04.033. Epub 2016 May 12. Cell. 2016. PMID: 27180906 Free PMC article.
Sox2 Suppresses Gastric Tumorigenesis in Mice.
Sarkar A, Huebner AJ, Sulahian R, Anselmo A, Xu X, Flattery K, Desai N, Sebastian C, Yram MA, Arnold K, Rivera M, Mostoslavsky R, Bronson R, Bass AJ, Sadreyev R, Shivdasani RA, Hochedlinger K. Sarkar A, et al. Cell Rep. 2016 Aug 16;16(7):1929-41. doi: 10.1016/j.celrep.2016.07.034. Epub 2016 Aug 4. Cell Rep. 2016. PMID: 27498859 Free article.
T Cell Immune Deficiency in zap70 Mutant Zebrafish.
Moore JC, Mulligan TS, Yordán NT, Castranova D, Pham VN, Tang Q, Lobbardi R, Anselmo A, Liwski RS, Berman JN, Sadreyev RI, Weinstein BM, Langenau DM. Moore JC, et al. Among authors: sadreyev ri. Mol Cell Biol. 2016 Nov 14;36(23):2868-2876. doi: 10.1128/MCB.00281-16. Print 2016 Dec 1. Mol Cell Biol. 2016. PMID: 27601584 Free PMC article.
184 results