MacNair CR - Search Results

1

Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens.

Carfrae LA, MacNair CR, Brown CM, Tsai CN, Weber BS, Zlitni S, Rao VN, Chun J, Junop MS, Coombes BK, Brown ED. Carfrae LA, et al. Among authors: macnair cr. Nat Microbiol. 2020 Jan;5(1):93-101. doi: 10.1038/s41564-019-0595-2. Epub 2019 Oct 28. Nat Microbiol. 2020. PMID: 31659298

2

A cell-based approach to characterize antimicrobial compounds through kinetic dose response.

MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED. MacNair CR, et al. Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053. Epub 2016 Sep 22. Bioorg Med Chem. 2016. PMID: 27713016

3

The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.

Côté JP, French S, Gehrke SS, MacNair CR, Mangat CS, Bharat A, Brown ED. Côté JP, et al. Among authors: macnair cr. mBio. 2016 Nov 22;7(6):e01714-16. doi: 10.1128/mBio.01714-16. mBio. 2016. PMID: 27879333 Free PMC article.

4

Author Correction for Côté et al., The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.

Côté JP, French S, Gehrke SS, MacNair CR, Mangat CS, Bharat A, Brown ED. Côté JP, et al. Among authors: macnair cr. mBio. 2016 Dec 20;7(6):e02138-16. doi: 10.1128/mBio.02138-16. mBio. 2016. PMID: 27999168 Free PMC article. No abstract available.

5

Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.

Stokes JM, MacNair CR, Ilyas B, French S, Côté JP, Bouwman C, Farha MA, Sieron AO, Whitfield C, Coombes BK, Brown ED. Stokes JM, et al. Among authors: macnair cr. Nat Microbiol. 2017 Mar 6;2:17028. doi: 10.1038/nmicrobiol.2017.28. Nat Microbiol. 2017. PMID: 28263303 Free PMC article.

6

Exploiting the Sensitivity of Nutrient Transporter Deletion Strains in Discovery of Natural Product Antimetabolites.

Gehrke SS, Kumar G, Yokubynas NA, Côté JP, Wang W, French S, MacNair CR, Wright GD, Brown ED. Gehrke SS, et al. Among authors: macnair cr. ACS Infect Dis. 2017 Dec 8;3(12):955-965. doi: 10.1021/acsinfecdis.7b00149. Epub 2017 Nov 7. ACS Infect Dis. 2017. PMID: 29069544

7

Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium.

Ellis MJ, Carfrae LA, Macnair CR, Trussler RS, Brown ED, Haniford DB. Ellis MJ, et al. Among authors: macnair cr. RNA Biol. 2018 Feb 1;15(2):176-181. doi: 10.1080/15476286.2017.1403001. Epub 2017 Dec 8. RNA Biol. 2018. PMID: 29120256 Free PMC article.

8

Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.

MacNair CR, Stokes JM, Carfrae LA, Fiebig-Comyn AA, Coombes BK, Mulvey MR, Brown ED. MacNair CR, et al. Nat Commun. 2018 Jan 31;9(1):458. doi: 10.1038/s41467-018-02875-z. Nat Commun. 2018. PMID: 29386620 Free PMC article.

9

Creative targeting of the Gram-negative outer membrane in antibiotic discovery.

MacNair CR, Tsai CN, Brown ED. MacNair CR, et al. Ann N Y Acad Sci. 2020 Jan;1459(1):69-85. doi: 10.1111/nyas.14280. Epub 2019 Nov 24. Ann N Y Acad Sci. 2020. PMID: 31762048 Review.

10

Uncovering the Hidden Antibiotic Potential of Cannabis.

Farha MA, El-Halfawy OM, Gale RT, MacNair CR, Carfrae LA, Zhang X, Jentsch NG, Magolan J, Brown ED. Farha MA, et al. Among authors: macnair cr. ACS Infect Dis. 2020 Mar 13;6(3):338-346. doi: 10.1021/acsinfecdis.9b00419. Epub 2020 Feb 6. ACS Infect Dis. 2020. PMID: 32017534

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