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4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Jeong SY, Hogarth P, Placzek A, Gregory AM, Fox R, Zhen D, Hamada J, van der Zwaag M, Lambrechts R, Jin H, Nilsen A, Cobb J, Pham T, Gray N, Ralle M, Duffy M, Schwanemann L, Rai P, Freed A, Wakeman K, Woltjer RL, Sibon OC, Hayflick SJ. Jeong SY, et al. Among authors: placzek a. EMBO Mol Med. 2019 Dec;11(12):e10489. doi: 10.15252/emmm.201910489. Epub 2019 Oct 29. EMBO Mol Med. 2019. PMID: 31660701 Free PMC article.
Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.
Ma H, Yang F, Butler MR, Belcher J, Redmond TM, Placzek AT, Scanlan TS, Ding XQ. Ma H, et al. FASEB J. 2017 Aug;31(8):3425-3438. doi: 10.1096/fj.201601166RR. Epub 2017 Apr 20. FASEB J. 2017. PMID: 28428265 Free PMC article.
Our findings support the view that inhibition of TR locally in the retina is a therapeutic strategy for retinal degeneration management.-Ma, H., Yang, F., Butler, M. R., Belcher, J., Redmond, T. M., Placzek, A. T., Scanlan, T. S., Ding, X.-Q. Inhibition of th …
Our findings support the view that inhibition of TR locally in the retina is a therapeutic strategy for retinal degeneration manageme …
Increasing Thyromimetic Potency through Halogen Substitution.
Devereaux J, Ferrara SJ, Banerji T, Placzek AT, Scanlan TS. Devereaux J, et al. ChemMedChem. 2016 Nov 7;11(21):2459-2465. doi: 10.1002/cmdc.201600408. Epub 2016 Oct 12. ChemMedChem. 2016. PMID: 27731931 Free PMC article.
62 results