Özdinler PH - Search Results

1

MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology.

Jara JH, Gautam M, Kocak N, Xie EF, Mao Q, Bigio EH, Özdinler PH. Jara JH, et al. Among authors: ozdinler ph. J Neuroinflammation. 2019 Oct 30;16(1):196. doi: 10.1186/s12974-019-1589-y. J Neuroinflammation. 2019. PMID: 31666087 Free PMC article.

2

AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS.

Jara JH, Villa SR, Khan NA, Bohn MC, Ozdinler PH. Jara JH, et al. Among authors: ozdinler ph. Neurobiol Dis. 2012 Aug;47(2):174-83. doi: 10.1016/j.nbd.2012.03.036. Epub 2012 Apr 11. Neurobiol Dis. 2012. PMID: 22521461 Free PMC article.

3

eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model.

Yasvoina MV, Genç B, Jara JH, Sheets PL, Quinlan KA, Milosevic A, Shepherd GM, Heckman CJ, Özdinler PH. Yasvoina MV, et al. Among authors: ozdinler ph. J Neurosci. 2013 May 1;33(18):7890-904. doi: 10.1523/JNEUROSCI.2787-12.2013. J Neurosci. 2013. PMID: 23637180 Free PMC article.

4

Could dysregulation of UPS be a common underlying mechanism for cancer and neurodegeneration? Lessons from UCHL1.

Jara JH, Frank DD, Özdinler PH. Jara JH, et al. Among authors: ozdinler ph. Cell Biochem Biophys. 2013 Sep;67(1):45-53. doi: 10.1007/s12013-013-9631-7. Cell Biochem Biophys. 2013. PMID: 23695785 Review.

5

Moving forward in clinical trials for ALS: motor neurons lead the way please.

Genç B, Özdinler PH. Genç B, et al. Among authors: ozdinler ph. Drug Discov Today. 2014 Apr;19(4):441-9. doi: 10.1016/j.drudis.2013.10.014. Epub 2013 Oct 27. Drug Discov Today. 2014. PMID: 24171950 Free PMC article. Review.

6

Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease.

Jara JH, Genç B, Klessner JL, Ozdinler PH. Jara JH, et al. Among authors: ozdinler ph. Front Neuroanat. 2014 Mar 26;8:16. doi: 10.3389/fnana.2014.00016. eCollection 2014. Front Neuroanat. 2014. PMID: 24723858 Free PMC article. Review.

7

Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function.

Jara JH, Genç B, Cox GA, Bohn MC, Roos RP, Macklis JD, Ulupınar E, Özdinler PH. Jara JH, et al. Among authors: ozdinler ph. Cereb Cortex. 2015 Nov;25(11):4259-72. doi: 10.1093/cercor/bhu318. Epub 2015 Jan 16. Cereb Cortex. 2015. PMID: 25596590 Free PMC article.

8

Visualization of Sensory Neurons and Their Projections in an Upper Motor Neuron Reporter Line.

Genç B, Lagrimas AK, Kuru P, Hess R, Tu MW, Menichella DM, Miller RJ, Paller AS, Özdinler PH. Genç B, et al. Among authors: ozdinler ph. PLoS One. 2015 Jul 29;10(7):e0132815. doi: 10.1371/journal.pone.0132815. eCollection 2015. PLoS One. 2015. PMID: 26222784 Free PMC article.

9

Healthy and diseased corticospinal motor neurons are selectively transduced upon direct AAV2-2 injection into the motor cortex.

Jara JH, Stanford MJ, Zhu Y, Tu M, Hauswirth WW, Bohn MC, DeVries SH, Özdinler PH. Jara JH, et al. Among authors: ozdinler ph. Gene Ther. 2016 Mar;23(3):272-82. doi: 10.1038/gt.2015.112. Epub 2016 Jan 21. Gene Ther. 2016. PMID: 26704722 Free PMC article.

10

Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms.

Gautam M, Jara JH, Sekerkova G, Yasvoina MV, Martina M, Özdinler PH. Gautam M, et al. Among authors: ozdinler ph. Hum Mol Genet. 2016 Mar 15;25(6):1074-87. doi: 10.1093/hmg/ddv631. Epub 2016 Jan 10. Hum Mol Genet. 2016. PMID: 26755825 Free PMC article.

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