Jara JH - Search Results

1

MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology.

Jara JH, Gautam M, Kocak N, Xie EF, Mao Q, Bigio EH, Özdinler PH. Jara JH, et al. J Neuroinflammation. 2019 Oct 30;16(1):196. doi: 10.1186/s12974-019-1589-y. J Neuroinflammation. 2019. PMID: 31666087 Free PMC article.

2

AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS.

Jara JH, Villa SR, Khan NA, Bohn MC, Ozdinler PH. Jara JH, et al. Neurobiol Dis. 2012 Aug;47(2):174-83. doi: 10.1016/j.nbd.2012.03.036. Epub 2012 Apr 11. Neurobiol Dis. 2012. PMID: 22521461 Free PMC article.

3

Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms.

Gautam M, Jara JH, Sekerkova G, Yasvoina MV, Martina M, Özdinler PH. Gautam M, et al. Among authors: jara jh. Hum Mol Genet. 2016 Mar 15;25(6):1074-87. doi: 10.1093/hmg/ddv631. Epub 2016 Jan 10. Hum Mol Genet. 2016. PMID: 26755825 Free PMC article.

4

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS.

Genç B, Jara JH, Lagrimas AK, Pytel P, Roos RP, Mesulam MM, Geula C, Bigio EH, Özdinler PH. Genç B, et al. Among authors: jara jh. Sci Rep. 2017 Feb 6;7:41765. doi: 10.1038/srep41765. Sci Rep. 2017. PMID: 28165465 Free PMC article.

5

Evidence for an early innate immune response in the motor cortex of ALS.

Jara JH, Genç B, Stanford MJ, Pytel P, Roos RP, Weintraub S, Mesulam MM, Bigio EH, Miller RJ, Özdinler PH. Jara JH, et al. J Neuroinflammation. 2017 Jun 26;14(1):129. doi: 10.1186/s12974-017-0896-4. J Neuroinflammation. 2017. PMID: 28651542 Free PMC article.

6

Mitochondria, ER, and nuclear membrane defects reveal early mechanisms for upper motor neuron vulnerability with respect to TDP-43 pathology.

Gautam M, Jara JH, Kocak N, Rylaarsdam LE, Kim KD, Bigio EH, Hande Özdinler P. Gautam M, et al. Among authors: jara jh. Acta Neuropathol. 2019 Jan;137(1):47-69. doi: 10.1007/s00401-018-1934-8. Epub 2018 Nov 19. Acta Neuropathol. 2019. PMID: 30450515 Free PMC article.

7

Healthy and diseased corticospinal motor neurons are selectively transduced upon direct AAV2-2 injection into the motor cortex.

Jara JH, Stanford MJ, Zhu Y, Tu M, Hauswirth WW, Bohn MC, DeVries SH, Özdinler PH. Jara JH, et al. Gene Ther. 2016 Mar;23(3):272-82. doi: 10.1038/gt.2015.112. Epub 2016 Jan 21. Gene Ther. 2016. PMID: 26704722 Free PMC article.

8

eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model.

Yasvoina MV, Genç B, Jara JH, Sheets PL, Quinlan KA, Milosevic A, Shepherd GM, Heckman CJ, Özdinler PH. Yasvoina MV, et al. Among authors: jara jh. J Neurosci. 2013 May 1;33(18):7890-904. doi: 10.1523/JNEUROSCI.2787-12.2013. J Neurosci. 2013. PMID: 23637180 Free PMC article.

9

Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease.

Jara JH, Genç B, Klessner JL, Ozdinler PH. Jara JH, et al. Front Neuroanat. 2014 Mar 26;8:16. doi: 10.3389/fnana.2014.00016. eCollection 2014. Front Neuroanat. 2014. PMID: 24723858 Free PMC article. Review.

10

Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function.

Jara JH, Genç B, Cox GA, Bohn MC, Roos RP, Macklis JD, Ulupınar E, Özdinler PH. Jara JH, et al. Cereb Cortex. 2015 Nov;25(11):4259-72. doi: 10.1093/cercor/bhu318. Epub 2015 Jan 16. Cereb Cortex. 2015. PMID: 25596590 Free PMC article.

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