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Page 1
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs.
Flavahan WA, Drier Y, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD, Bernstein BE. Flavahan WA, et al. Among authors: johnstone se. Nature. 2019 Nov;575(7781):229-233. doi: 10.1038/s41586-019-1668-3. Epub 2019 Oct 16. Nature. 2019. PMID: 31666694 Free PMC article.
Cohesin Loss Eliminates All Loop Domains.
Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL. Rao SSP, et al. Among authors: johnstone se. Cell. 2017 Oct 5;171(2):305-320.e24. doi: 10.1016/j.cell.2017.09.026. Cell. 2017. PMID: 28985562 Free PMC article.
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer.
Johnstone SE, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, Chen JH, Zou LS, Drier Y, Hecht V, Shoresh N, Selig MK, Lareau CA, Iyer S, Nguyen SC, Joyce EF, Hacohen N, Irizarry RA, Zhang B, Aryee MJ, Bernstein BE. Johnstone SE, et al. Cell. 2020 Sep 17;182(6):1474-1489.e23. doi: 10.1016/j.cell.2020.07.030. Epub 2020 Aug 24. Cell. 2020. PMID: 32841603 Free PMC article.
Epigenetic clocks, aging, and cancer.
Johnstone SE, Gladyshev VN, Aryee MJ, Bernstein BE. Johnstone SE, et al. Science. 2022 Dec 23;378(6626):1276-1277. doi: 10.1126/science.abn4009. Epub 2022 Dec 22. Science. 2022. PMID: 36548410
Modeling epigenetic lesions that cause gliomas.
Rahme GJ, Javed NM, Puorro KL, Xin S, Hovestadt V, Johnstone SE, Bernstein BE. Rahme GJ, et al. Among authors: johnstone se. Cell. 2023 Aug 17;186(17):3674-3685.e14. doi: 10.1016/j.cell.2023.06.022. Epub 2023 Jul 25. Cell. 2023. PMID: 37494934 Free PMC article.
Impact of supraphysiologic MDM2 expression on chromatin networks and therapeutic responses in sarcoma.
Bevill SM, Casaní-Galdón S, El Farran CA, Cytrynbaum EG, Macias KA, Oldeman SE, Oliveira KJ, Moore MM, Hegazi E, Adriaens C, Najm FJ, Demetri GD, Cohen S, Mullen JT, Riggi N, Johnstone SE, Bernstein BE. Bevill SM, et al. Among authors: johnstone se. Cell Genom. 2023 May 11;3(7):100321. doi: 10.1016/j.xgen.2023.100321. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492096 Free PMC article.
A DNA hypermethylation module for the stem/progenitor cell signature of cancer.
Easwaran H, Johnstone SE, Van Neste L, Ohm J, Mosbruger T, Wang Q, Aryee MJ, Joyce P, Ahuja N, Weisenberger D, Collisson E, Zhu J, Yegnasubramanian S, Matsui W, Baylin SB. Easwaran H, et al. Among authors: johnstone se. Genome Res. 2012 May;22(5):837-49. doi: 10.1101/gr.131169.111. Epub 2012 Mar 5. Genome Res. 2012. PMID: 22391556 Free PMC article.
20 results