Wooten DJ - Search Results

1

Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers.

Wooten DJ, Groves SM, Tyson DR, Liu Q, Lim JS, Albert R, Lopez CF, Sage J, Quaranta V. Wooten DJ, et al. PLoS Comput Biol. 2019 Oct 31;15(10):e1007343. doi: 10.1371/journal.pcbi.1007343. eCollection 2019 Oct. PLoS Comput Biol. 2019. PMID: 31671086 Free PMC article.

2

Novel Hybrid Phenotype Revealed in Small Cell Lung Cancer by a Transcription Factor Network Model That Can Explain Tumor Heterogeneity.

Udyavar AR, Wooten DJ, Hoeksema M, Bansal M, Califano A, Estrada L, Schnell S, Irish JM, Massion PP, Quaranta V. Udyavar AR, et al. Among authors: wooten dj. Cancer Res. 2017 Mar 1;77(5):1063-1074. doi: 10.1158/0008-5472.CAN-16-1467. Epub 2016 Dec 8. Cancer Res. 2017. PMID: 27932399 Free PMC article.

3

Mathematical models of cell phenotype regulation and reprogramming: Make cancer cells sensitive again!

Wooten DJ, Quaranta V. Wooten DJ, et al. Biochim Biophys Acta Rev Cancer. 2017 Apr;1867(2):167-175. doi: 10.1016/j.bbcan.2017.04.001. Epub 2017 Apr 7. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28396217 Free PMC article. Review.

4

synergy: a Python library for calculating, analyzing and visualizing drug combination synergy.

Wooten DJ, Albert R. Wooten DJ, et al. Bioinformatics. 2021 Jun 16;37(10):1473-1474. doi: 10.1093/bioinformatics/btaa826. Bioinformatics. 2021. PMID: 32960970

5

Charting the Fragmented Landscape of Drug Synergy.

Meyer CT, Wooten DJ, Lopez CF, Quaranta V. Meyer CT, et al. Among authors: wooten dj. Trends Pharmacol Sci. 2020 Apr;41(4):266-280. doi: 10.1016/j.tips.2020.01.011. Epub 2020 Feb 26. Trends Pharmacol Sci. 2020. PMID: 32113653 Free PMC article. Review.

6

MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery.

Wooten DJ, Meyer CT, Lubbock ALR, Quaranta V, Lopez CF. Wooten DJ, et al. Nat Commun. 2021 Jul 29;12(1):4607. doi: 10.1038/s41467-021-24789-z. Nat Commun. 2021. PMID: 34326325 Free PMC article.

7

Mathematical modeling of the Candida albicans yeast to hyphal transition reveals novel control strategies.

Wooten DJ, Zañudo JGT, Murrugarra D, Perry AM, Dongari-Bagtzoglou A, Laubenbacher R, Nobile CJ, Albert R. Wooten DJ, et al. PLoS Comput Biol. 2021 Mar 29;17(3):e1008690. doi: 10.1371/journal.pcbi.1008690. eCollection 2021 Mar. PLoS Comput Biol. 2021. PMID: 33780439 Free PMC article.

8

Data-Driven Math Model of FLT3-ITD Acute Myeloid Leukemia Reveals Potential Therapeutic Targets.

Wooten DJ, Gebru M, Wang HG, Albert R. Wooten DJ, et al. J Pers Med. 2021 Mar 11;11(3):193. doi: 10.3390/jpm11030193. J Pers Med. 2021. PMID: 33799721 Free PMC article.

9

Ventricular-Subventricular Zone Contact by Glioblastoma is Not Associated with Molecular Signatures in Bulk Tumor Data.

Mistry AM, Wooten DJ, Davis LT, Mobley BC, Quaranta V, Ihrie RA. Mistry AM, et al. Among authors: wooten dj. Sci Rep. 2019 Feb 12;9(1):1842. doi: 10.1038/s41598-018-37734-w. Sci Rep. 2019. PMID: 30755636 Free PMC article.

10

Quantifying Drug Combination Synergy along Potency and Efficacy Axes.

Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V. Meyer CT, et al. Among authors: wooten dj. Cell Syst. 2019 Feb 27;8(2):97-108.e16. doi: 10.1016/j.cels.2019.01.003. Epub 2019 Feb 20. Cell Syst. 2019. PMID: 30797775 Free PMC article.

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