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TAK-994 Mechanistic Investigation into Drug-Induced Liver Injury.
Shinozawa T, Miyamoto K, Baker KS, Faber SC, Flores R, Uetrecht J, von Hehn C, Yukawa T, Tohyama K, Kadali H, von Grotthuss M, Sudo Y, Smith EN, Diogo D, Zhu AZX, Dragan Y, Cebers G, Wagoner MP. Shinozawa T, et al. Among authors: wagoner mp. Toxicol Sci. 2025 Jan 9:kfaf003. doi: 10.1093/toxsci/kfaf003. Online ahead of print. Toxicol Sci. 2025. PMID: 39786842
Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury.
Carr DF, Ayehunie S, Davies A, Duckworth CA, French S, Hall N, Hussain S, Mellor HR, Norris A, Park BK, Penrose A, Pritchard DM, Probert CS, Ramaiah S, Sadler C, Schmitt M, Shaw A, Sidaway JE, Vries RG, Wagoner M, Pirmohamed M. Carr DF, et al. Among authors: wagoner m. Pharmacol Ther. 2017 Apr;172:181-194. doi: 10.1016/j.pharmthera.2017.01.002. Epub 2017 Jan 27. Pharmacol Ther. 2017. PMID: 28132905 Review.
Early prediction of polymyxin-induced nephrotoxicity with next-generation urinary kidney injury biomarkers.
Keirstead ND, Wagoner MP, Bentley P, Blais M, Brown C, Cheatham L, Ciaccio P, Dragan Y, Ferguson D, Fikes J, Galvin M, Gupta A, Hale M, Johnson N, Luo W, McGrath F, Pietras M, Price S, Sathe AG, Sasaki JC, Snow D, Walsky RL, Kern G. Keirstead ND, et al. Among authors: wagoner mp. Toxicol Sci. 2014 Feb;137(2):278-91. doi: 10.1093/toxsci/kft247. Epub 2013 Nov 4. Toxicol Sci. 2014. PMID: 24189134
A Reduction in B, T, and Natural Killer Cells Expressing CD38 by TAK-079 Inhibits the Induction and Progression of Collagen-Induced Arthritis in Cynomolgus Monkeys.
Korver W, Carsillo M, Yuan J, Idamakanti N, Wagoner M, Shi P, Xia CQ, Smithson G, McLean L, Zalevsky J, Fedyk ER. Korver W, et al. Among authors: wagoner m. J Pharmacol Exp Ther. 2019 Aug;370(2):182-196. doi: 10.1124/jpet.119.256602. Epub 2019 May 13. J Pharmacol Exp Ther. 2019. PMID: 31085699
192 results