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Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.
He Y, Schreiber K, Wolf SP, Wen F, Steentoft C, Zerweck J, Steiner M, Sharma P, Shepard HM, Posey A, June CH, Mandel U, Clausen H, Leisegang M, Meredith SC, Kranz DM, Schreiber H. He Y, et al. Among authors: shepard hm. JCI Insight. 2019 Dec 5;4(23):e135306. doi: 10.1172/jci.insight.135306. JCI Insight. 2019. PMID: 31801912 Free PMC article. No abstract available.
Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts.
Sarup J, Jin P, Turin L, Bai X, Beryt M, Brdlik C, Higaki JN, Jorgensen B, Lau FW, Lindley P, Liu J, Ni I, Rozzelle J, Kumari R, Watson SA, Zhang J, Shepard HM. Sarup J, et al. Among authors: shepard hm. Mol Cancer Ther. 2008 Oct;7(10):3223-36. doi: 10.1158/1535-7163.MCT-07-2151. Mol Cancer Ther. 2008. PMID: 18852126
95 results