Connolly PJ - Search Results

1

Discovery and optimization of a series of small-molecule allosteric inhibitors of MALT1 protease.

Lu T, Connolly PJ, Philippar U, Sun W, Cummings MD, Barbay K, Gys L, Van Nuffel L, Austin N, Bekkers M, Shen F, Cai A, Attar R, Meerpoel L, Edwards J. Lu T, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2019 Dec 1;29(23):126743. doi: 10.1016/j.bmcl.2019.126743. Epub 2019 Oct 17. Bioorg Med Chem Lett. 2019. PMID: 31678006

2

Synthesis and discovery of pyrazine-pyridine biheteroaryl as a novel series of potent vascular endothelial growth factor receptor-2 inhibitors.

Kuo GH, Wang A, Emanuel S, Deangelis A, Zhang R, Connolly PJ, Murray WV, Gruninger RH, Sechler J, Fuentes-Pesquera A, Johnson D, Middleton SA, Jolliffe L, Chen X. Kuo GH, et al. Among authors: connolly pj. J Med Chem. 2005 Mar 24;48(6):1886-900. doi: 10.1021/jm040099a. J Med Chem. 2005. PMID: 15771433

3

3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.

Lin R, Lu Y, Wetter SK, Connolly PJ, Turchi IJ, Murray WV, Emanuel SL, Gruninger RH, Fuentes-Pesquera AR, Adams M, Pandey N, Moreno-Mazza S, Middleton SA, Jolliffe LK. Lin R, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2005 May 2;15(9):2221-4. doi: 10.1016/j.bmcl.2005.03.024. Bioorg Med Chem Lett. 2005. PMID: 15837297

4

Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.

Kuo GH, Deangelis A, Emanuel S, Wang A, Zhang Y, Connolly PJ, Chen X, Gruninger RH, Rugg C, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV. Kuo GH, et al. Among authors: connolly pj. J Med Chem. 2005 Jul 14;48(14):4535-46. doi: 10.1021/jm040214h. J Med Chem. 2005. PMID: 15999992

5

Synthesis of 2-amino-4-(7-azaindol-3-yl)pyrimidines as cyclin dependent kinase 1 (CDK1) inhibitors.

Huang S, Li R, Connolly PJ, Emanuel S, Middleton SA. Huang S, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4818-21. doi: 10.1016/j.bmcl.2006.06.073. Epub 2006 Jul 25. Bioorg Med Chem Lett. 2006. PMID: 16870444

6

Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors.

Lin R, Chiu G, Yu Y, Connolly PJ, Li S, Lu Y, Adams M, Fuentes-Pesquera AR, Emanuel SL, Greenberger LM. Lin R, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4557-61. doi: 10.1016/j.bmcl.2007.05.092. Epub 2007 Jun 6. Bioorg Med Chem Lett. 2007. PMID: 17574416

7

Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases.

Xu G, Searle LL, Hughes TV, Beck AK, Connolly PJ, Abad MC, Neeper MP, Struble GT, Springer BA, Emanuel SL, Gruninger RH, Pandey N, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Greenberger LM. Xu G, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3495-9. doi: 10.1016/j.bmcl.2008.05.024. Epub 2008 May 10. Bioorg Med Chem Lett. 2008. PMID: 18508264

8

Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.

Lin R, Johnson SG, Connolly PJ, Wetter SK, Binnun E, Hughes TV, Murray WV, Pandey NB, Moreno-Mazza SJ, Adams M, Fuentes-Pesquera AR, Middleton SA. Lin R, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2333-7. doi: 10.1016/j.bmcl.2009.02.067. Epub 2009 Feb 21. Bioorg Med Chem Lett. 2009. PMID: 19286381

9

4-aminopyrimidine-5-carbaldehyde oximes as potent VEGFR-2 inhibitors. Part II.

Huang S, Li R, LaMontagne KR, Greenberger LM, Connolly PJ. Huang S, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2011 Mar 15;21(6):1815-8. doi: 10.1016/j.bmcl.2011.01.053. Epub 2011 Jan 21. Bioorg Med Chem Lett. 2011. PMID: 21316232

10

A selective small molecule NOP (ORL-1 receptor) partial agonist for the treatment of anxiety.

Ross TM, Battista K, Bignan GC, Brenneman DE, Connolly PJ, Liu J, Middleton SA, Orsini M, Reitz AB, Rosenthal DI, Scott MK, Vaidya AH. Ross TM, et al. Among authors: connolly pj. Bioorg Med Chem Lett. 2015 Feb 1;25(3):602-6. doi: 10.1016/j.bmcl.2014.12.015. Epub 2014 Dec 17. Bioorg Med Chem Lett. 2015. PMID: 25556095

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

142 results

Search Page

Filters