Ramsden NG - Search Results

1

Inhibition of HIV replication by amino-sugar derivatives.

Fleet GW, Karpas A, Dwek RA, Fellows LE, Tyms AS, Petursson S, Namgoong SK, Ramsden NG, Smith PW, Son JC, et al. Fleet GW, et al. Among authors: ramsden ng. FEBS Lett. 1988 Sep 12;237(1-2):128-32. doi: 10.1016/0014-5793(88)80185-6. FEBS Lett. 1988. PMID: 3169233 Free article.

2

Aminosugar derivatives as potential anti-human immunodeficiency virus agents.

Karpas A, Fleet GW, Dwek RA, Petursson S, Namgoong SK, Ramsden NG, Jacob GS, Rademacher TW. Karpas A, et al. Among authors: ramsden ng. Proc Natl Acad Sci U S A. 1988 Dec;85(23):9229-33. doi: 10.1073/pnas.85.23.9229. Proc Natl Acad Sci U S A. 1988. PMID: 3264071 Free PMC article.

3

Synthesis of the enantiomers of 6-epicastanospermine and 1,6-diepicastanospermine from D- and L-gulonolactone.

Fleet GW, Ramsden NG, Nash RJ, Fellows LE, Jacob GS, Molyneux RJ, di Bello IC, Winchester B. Fleet GW, et al. Among authors: ramsden ng. Carbohydr Res. 1990 Sep 19;205:269-82. doi: 10.1016/0008-6215(90)80146-t. Carbohydr Res. 1990. PMID: 2276139

4

The structural basis of the inhibition of human glycosidases by castanospermine analogues.

Winchester BG, Cenci di Bello I, Richardson AC, Nash RJ, Fellows LE, Ramsden NG, Fleet G. Winchester BG, et al. Among authors: ramsden ng. Biochem J. 1990 Jul 1;269(1):227-31. doi: 10.1042/bj2690227. Biochem J. 1990. PMID: 2115770 Free PMC article.

5

Glucose analogue inhibitors of glycogen phosphorylase: the design of potential drugs for diabetes.

Martin JL, Veluraja K, Ross K, Johnson LN, Fleet GW, Ramsden NG, Bruce I, Orchard MG, Oikonomakos NG, Papageorgiou AC, et al. Martin JL, et al. Among authors: ramsden ng. Biochemistry. 1991 Oct 22;30(42):10101-16. doi: 10.1021/bi00106a006. Biochemistry. 1991. PMID: 1931942

6

Anomeric specificity of D-xylose isomerase.

Collyer CA, Goldberg JD, Viehmann H, Blow DM, Ramsden NG, Fleet GW, Montgomery FJ, Grice P. Collyer CA, et al. Among authors: ramsden ng. Biochemistry. 1992 Dec 8;31(48):12211-8. doi: 10.1021/bi00163a034. Biochemistry. 1992. PMID: 1457418

7

SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors.

Bell K, Sunose M, Ellard K, Cansfield A, Taylor J, Miller W, Ramsden N, Bergamini G, Neubauer G. Bell K, et al. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5257-63. doi: 10.1016/j.bmcl.2012.06.049. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22819766

8

A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.

Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Müller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. Bergamini G, et al. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957. Nat Chem Biol. 2012. PMID: 22544264

9

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.

Sunose M, Bell K, Ellard K, Bergamini G, Neubauer G, Werner T, Ramsden N. Sunose M, et al. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4613-8. doi: 10.1016/j.bmcl.2012.05.090. Epub 2012 Jun 5. Bioorg Med Chem Lett. 2012. PMID: 22726925

10

Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation.

Ellard K, Sunose M, Bell K, Ramsden N, Bergamini G, Neubauer G. Ellard K, et al. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4546-9. doi: 10.1016/j.bmcl.2012.05.121. Epub 2012 Jun 9. Bioorg Med Chem Lett. 2012. PMID: 22738635

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