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Page 1
Changing POU dimerization preferences converts Oct6 into a pluripotency inducer.
Jerabek S, Ng CK, Wu G, Arauzo-Bravo MJ, Kim KP, Esch D, Malik V, Chen Y, Velychko S, MacCarthy CM, Yang X, Cojocaru V, Schöler HR, Jauch R. Jerabek S, et al. Among authors: maccarthy cm. EMBO Rep. 2017 Feb;18(2):319-333. doi: 10.15252/embr.201642958. Epub 2016 Dec 22. EMBO Rep. 2017. PMID: 28007765 Free PMC article.
Nucleosomal DNA Dynamics Mediate Oct4 Pioneer Factor Binding.
Huertas J, MacCarthy CM, Schöler HR, Cojocaru V. Huertas J, et al. Among authors: maccarthy cm. Biophys J. 2020 May 5;118(9):2280-2296. doi: 10.1016/j.bpj.2019.12.038. Epub 2020 Jan 16. Biophys J. 2020. PMID: 32027821 Free PMC article.
Reprogramming competence of OCT factors is determined by transactivation domains.
Kim KP, Wu Y, Yoon J, Adachi K, Wu G, Velychko S, MacCarthy CM, Shin B, Röpke A, Arauzo-Bravo MJ, Stehling M, Han DW, Gao Y, Kim J, Gao S, Schöler HR. Kim KP, et al. Among authors: maccarthy cm. Sci Adv. 2020 Sep 2;6(36):eaaz7364. doi: 10.1126/sciadv.aaz7364. Print 2020 Sep. Sci Adv. 2020. PMID: 32917606 Free PMC article.
A balanced Oct4 interactome is crucial for maintaining pluripotency.
Han D, Wu G, Chen R, Drexler HCA, MacCarthy CM, Kim KP, Adachi K, Gerovska D, Mavrommatis L, Bedzhov I, Araúzo-Bravo MJ, Schöler HR. Han D, et al. Among authors: maccarthy cm. Sci Adv. 2022 Feb 18;8(7):eabe4375. doi: 10.1126/sciadv.abe4375. Epub 2022 Feb 16. Sci Adv. 2022. PMID: 35171666 Free PMC article.
OCT4 interprets and enhances nucleosome flexibility.
MacCarthy CM, Huertas J, Ortmeier C, Vom Bruch H, Tan DS, Reinke D, Sander A, Bergbrede T, Jauch R, Schöler HR, Cojocaru V. MacCarthy CM, et al. Nucleic Acids Res. 2022 Oct 14;50(18):10311-10327. doi: 10.1093/nar/gkac755. Nucleic Acids Res. 2022. PMID: 36130732 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36782801
16 results