Liu DR - Search Results

1

Adenine base editing in an adult mouse model of tyrosinaemia.

Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W. Song CQ, et al. Among authors: liu dr. Nat Biomed Eng. 2020 Jan;4(1):125-130. doi: 10.1038/s41551-019-0357-8. Epub 2019 Feb 25. Nat Biomed Eng. 2020. PMID: 31740768 Free PMC article.

2

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification.

Guilinger JP, Thompson DB, Liu DR. Guilinger JP, et al. Among authors: liu dr. Nat Biotechnol. 2014 Jun;32(6):577-582. doi: 10.1038/nbt.2909. Epub 2014 Apr 25. Nat Biotechnol. 2014. PMID: 24770324 Free PMC article.

3

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. Komor AC, et al. Among authors: liu dr. Nature. 2016 May 19;533(7603):420-4. doi: 10.1038/nature17946. Epub 2016 Apr 20. Nature. 2016. PMID: 27096365 Free PMC article.

4

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Kim YB, et al. Among authors: liu dr. Nat Biotechnol. 2017 Apr;35(4):371-376. doi: 10.1038/nbt.3803. Epub 2017 Feb 13. Nat Biotechnol. 2017. PMID: 28191901 Free PMC article.

5

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.

Rees HA, Komor AC, Yeh WH, Caetano-Lopes J, Warman M, Edge ASB, Liu DR. Rees HA, et al. Among authors: liu dr. Nat Commun. 2017 Jun 6;8:15790. doi: 10.1038/ncomms15790. Nat Commun. 2017. PMID: 28585549 Free PMC article.

6

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.

Tang W, Hu JH, Liu DR. Tang W, et al. Among authors: liu dr. Nat Commun. 2017 Jun 28;8:15939. doi: 10.1038/ncomms15939. Nat Commun. 2017. PMID: 28656978 Free PMC article.

7

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Komor AC, et al. Among authors: liu dr. Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug. Sci Adv. 2017. PMID: 28875174 Free PMC article.

8

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR. Gaudelli NM, et al. Among authors: liu dr. Nature. 2017 Nov 23;551(7681):464-471. doi: 10.1038/nature24644. Epub 2017 Oct 25. Nature. 2017. PMID: 29160308 Free PMC article.

9

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.

Gao X, Tao Y, Lamas V, Huang M, Yeh WH, Pan B, Hu YJ, Hu JH, Thompson DB, Shu Y, Li Y, Wang H, Yang S, Xu Q, Polley DB, Liberman MC, Kong WJ, Holt JR, Chen ZY, Liu DR. Gao X, et al. Among authors: liu dr. Nature. 2018 Jan 11;553(7687):217-221. doi: 10.1038/nature25164. Epub 2017 Dec 20. Nature. 2018. PMID: 29258297 Free PMC article.

10

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.

Hu JH, Miller SM, Geurts MH, Tang W, Chen L, Sun N, Zeina CM, Gao X, Rees HA, Lin Z, Liu DR. Hu JH, et al. Among authors: liu dr. Nature. 2018 Apr 5;556(7699):57-63. doi: 10.1038/nature26155. Epub 2018 Feb 28. Nature. 2018. PMID: 29512652 Free PMC article.

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