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Page 1
A causal role for TRESK loss of function in migraine mechanisms.
Pettingill P, Weir GA, Wei T, Wu Y, Flower G, Lalic T, Handel A, Duggal G, Chintawar S, Cheung J, Arunasalam K, Couper E, Haupt LM, Griffiths LR, Bassett A, Cowley SA, Cader MZ. Pettingill P, et al. Among authors: cowley sa. Brain. 2019 Dec 1;142(12):3852-3867. doi: 10.1093/brain/awz342. Brain. 2019. PMID: 31742594 Free PMC article.
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.
Handel AE, Chintawar S, Lalic T, Whiteley E, Vowles J, Giustacchini A, Argoud K, Sopp P, Nakanishi M, Bowden R, Cowley S, Newey S, Akerman C, Ponting CP, Cader MZ. Handel AE, et al. Hum Mol Genet. 2016 Mar 1;25(5):989-1000. doi: 10.1093/hmg/ddv637. Epub 2016 Jan 5. Hum Mol Genet. 2016. PMID: 26740550 Free PMC article.
C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Dafinca R, Scaber J, Ababneh N, Lalic T, Weir G, Christian H, Vowles J, Douglas AG, Fletcher-Jones A, Browne C, Nakanishi M, Turner MR, Wade-Martins R, Cowley SA, Talbot K. Dafinca R, et al. Among authors: cowley sa. Stem Cells. 2016 Aug;34(8):2063-78. doi: 10.1002/stem.2388. Epub 2016 May 4. Stem Cells. 2016. PMID: 27097283 Free PMC article.
Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells.
Baud A, Wessely F, Mazzacuva F, McCormick J, Camuzeaux S, Heywood WE, Little D, Vowles J, Tuefferd M, Mosaku O, Lako M, Armstrong L, Webber C, Cader MZ, Peeters P, Gissen P, Cowley SA, Mills K. Baud A, et al. Among authors: cowley sa. Anal Chem. 2017 Feb 21;89(4):2440-2448. doi: 10.1021/acs.analchem.6b04368. Epub 2017 Feb 6. Anal Chem. 2017. PMID: 28192931
A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.
Haenseler W, Sansom SN, Buchrieser J, Newey SE, Moore CS, Nicholls FJ, Chintawar S, Schnell C, Antel JP, Allen ND, Cader MZ, Wade-Martins R, James WS, Cowley SA. Haenseler W, et al. Among authors: cowley sa. Stem Cell Reports. 2017 Jun 6;8(6):1727-1742. doi: 10.1016/j.stemcr.2017.05.017. Stem Cell Reports. 2017. PMID: 28591653 Free PMC article.
Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages.
Haenseler W, Zambon F, Lee H, Vowles J, Rinaldi F, Duggal G, Houlden H, Gwinn K, Wray S, Luk KC, Wade-Martins R, James WS, Cowley SA. Haenseler W, et al. Among authors: cowley sa. Sci Rep. 2017 Aug 21;7(1):9003. doi: 10.1038/s41598-017-09362-3. Sci Rep. 2017. PMID: 28827786 Free PMC article.
Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1.
Jonikas M, Madill M, Mathy A, Zekoll T, Zois CE, Wigfield S, Kurzawa-Akanbi M, Browne C, Sims D, Chinnery PF, Cowley SA, Tofaris GK. Jonikas M, et al. Among authors: cowley sa. Ann Neurol. 2018 May;83(5):915-925. doi: 10.1002/ana.25221. Epub 2018 Apr 25. Ann Neurol. 2018. PMID: 29604226 Free PMC article.
Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers.
Jarosz-Griffiths HH, Corbett NJ, Rowland HA, Fisher K, Jones AC, Baron J, Howell GJ, Cowley SA, Chintawar S, Cader MZ, Kellett KAB, Hooper NM. Jarosz-Griffiths HH, et al. Among authors: cowley sa. J Biol Chem. 2019 Apr 26;294(17):7085-7097. doi: 10.1074/jbc.RA118.005364. Epub 2019 Mar 14. J Biol Chem. 2019. PMID: 30872401 Free PMC article.
Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder.
Sanghani HR, Jagannath A, Humberstone T, Ebrahimjee F, Thomas JM, Churchill GC, Cipriani A, Attenburrow MJ, Perestenko OV, Cowley SA, Cader MZ, Peirson SN, Harrison PJ, Foster RG, Goodwin GM, Vasudevan SR. Sanghani HR, et al. Among authors: cowley sa. Mol Psychiatry. 2021 Sep;26(9):5252-5265. doi: 10.1038/s41380-020-0769-6. Epub 2020 May 13. Mol Psychiatry. 2021. PMID: 32404948 Free PMC article.
97 results