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Page 1
Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.
Figg WD Jr, McDonough MA, Chowdhury R, Nakashima Y, Zhang Z, Holt-Martyn JP, Krajnc A, Schofield CJ. Figg WD Jr, et al. ChemMedChem. 2021 Jul 6;16(13):2082-2088. doi: 10.1002/cmdc.202100133. Epub 2021 Apr 9. ChemMedChem. 2021. PMID: 33792169 Free PMC article.
Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors.
Holt-Martyn JP, Chowdhury R, Tumber A, Yeh TL, Abboud MI, Lippl K, Lohans CT, Langley GW, Figg W Jr, McDonough MA, Pugh CW, Ratcliffe PJ, Schofield CJ. Holt-Martyn JP, et al. Among authors: figg w jr. ChemMedChem. 2020 Feb 5;15(3):270-273. doi: 10.1002/cmdc.201900557. Epub 2019 Dec 3. ChemMedChem. 2020. PMID: 31751494 Free PMC article.
Studies on spiro[4.5]decanone prolyl hydroxylase domain inhibitors.
Holt-Martyn JP, Tumber A, Rahman MZ, Lippl K, Figg W Jr, McDonough MA, Chowdhury R, Schofield CJ. Holt-Martyn JP, et al. Among authors: figg w jr. Medchemcomm. 2019 Mar 1;10(4):500-504. doi: 10.1039/c8md00548f. eCollection 2019 Apr 1. Medchemcomm. 2019. PMID: 31057728 Free PMC article. Review.
Detectible mosaic truncating PPM1D mutations, age and breast cancer risk.
Machiela MJ, Myers TA, Lyons CJ, Koster R, Figg WD Jr, Colli LM, Jessop L, Ahearn TU, Freedman ND, García-Closas M, Chanock SJ. Machiela MJ, et al. Among authors: figg wd jr. J Hum Genet. 2019 Jun;64(6):545-550. doi: 10.1038/s10038-019-0589-1. Epub 2019 Mar 8. J Hum Genet. 2019. PMID: 30850729 Free PMC article.
Association Between Thiopurine S-Methyltransferase (TPMT) Genetic Variants and Infection in Pediatric Heart Transplant Recipients Treated With Azathioprine: A Multi-Institutional Analysis.
Green DJ, Duong SQ, Burckart GJ, Sissung T, Price DK, Figg WD Jr, Brooks MM, Chinnock R, Canter C, Addonizio L, Bernstein D, Naftel DC, Zeevi A, Kirklin JK, Webber SA, Feingold B. Green DJ, et al. Among authors: figg wd jr. J Pediatr Pharmacol Ther. 2018 Mar-Apr;23(2):106-110. doi: 10.5863/1551-6776-23.2.106. J Pediatr Pharmacol Ther. 2018. PMID: 29720911 Free PMC article.